Abstract
Discrete classification is common in Genomic Signal Processing applications, in particular in classification of discretized gene expression data, and in discrete gene expression prediction and the inference of boolean genomic regulatory networks. Once a discrete classifier is obtained from sample data, its performance must be evaluated through its classification error. In practice, error estimation methods must then be employed to obtain reliable estimates of the classification error based on the available data. Both classifier design and error estimation are complicated, in the case of Genomics, by the prevalence of small-sample data sets in such applications. This paper presents a broad review of the methodology of classification and error estimation for discrete data, in the context of Genomics, focusing on the study of performance in small sample scenarios, as well as asymptotic behavior.
Keywords: Genomics, classification, error estimation, discrete histogram rule, sampling distribution, resubstitution, leaveone-out, ensemble methods, coefficient of determination
Current Genomics
Title: Classification and Error Estimation for Discrete Data
Volume: 10 Issue: 7
Author(s): Ulisses M. Braga-Neto
Affiliation:
Keywords: Genomics, classification, error estimation, discrete histogram rule, sampling distribution, resubstitution, leaveone-out, ensemble methods, coefficient of determination
Abstract: Discrete classification is common in Genomic Signal Processing applications, in particular in classification of discretized gene expression data, and in discrete gene expression prediction and the inference of boolean genomic regulatory networks. Once a discrete classifier is obtained from sample data, its performance must be evaluated through its classification error. In practice, error estimation methods must then be employed to obtain reliable estimates of the classification error based on the available data. Both classifier design and error estimation are complicated, in the case of Genomics, by the prevalence of small-sample data sets in such applications. This paper presents a broad review of the methodology of classification and error estimation for discrete data, in the context of Genomics, focusing on the study of performance in small sample scenarios, as well as asymptotic behavior.
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Cite this article as:
Braga-Neto M. Ulisses, Classification and Error Estimation for Discrete Data, Current Genomics 2009; 10 (7) . https://dx.doi.org/10.2174/138920209789208228
DOI https://dx.doi.org/10.2174/138920209789208228 |
Print ISSN 1389-2029 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5488 |
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