Abstract
Asymmetric alkynylation of ketones can provide versatile chiral tertiary propargylic alcohols. A series of strategies have been achieved in the past few years. Relative optimal reaction conditions for obtaining the highest enantioselectivities and yields, as well as the practical scope of different types of catalytic systems are reviewed.
Current Organic Chemistry
Title: Recent Advance in Asymmetric Alkynylation of Ketones
Volume: 13 Issue: 15
Author(s): Li Lin and Rui Wang
Affiliation:
Abstract: Asymmetric alkynylation of ketones can provide versatile chiral tertiary propargylic alcohols. A series of strategies have been achieved in the past few years. Relative optimal reaction conditions for obtaining the highest enantioselectivities and yields, as well as the practical scope of different types of catalytic systems are reviewed.
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Cite this article as:
Lin Li and Wang Rui, Recent Advance in Asymmetric Alkynylation of Ketones, Current Organic Chemistry 2009; 13 (15) . https://dx.doi.org/10.2174/138527209789177725
DOI https://dx.doi.org/10.2174/138527209789177725 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
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