Colloidal Polymeric Nanoparticles and Brain Drug Delivery

Title: Colloidal Polymeric Nanoparticles and Brain Drug Delivery

Volume: 6 Issue: 3

Author(s): Najeh Maissar Khalil and Rubiana Mara Mainardes

Affiliation:

Keywords: Brain drug delivery, blood brain barrier, central nervous system, nanoparticles, biodegradable polymers

Abstract: The blood brain barrier protects the brain from harmful substances in the blood stream and has stopped the development of many powerful and interesting drugs candidates for central nervous system due to the low poor distribution and by efflux mechanisms. Many different approaches have been developed in order to overcome this barrier and the drug gain access to the brain. The polymeric nanoparticles are efficient colloidal systems that have been investigated to the brain drug delivery. This review will focus on the current strategies for brain drug delivery emphasizing the properties and characteristics of polymeric nanoparticles for this purpose.

Cite this article as:

Khalil Maissar Najeh and Mainardes Mara Rubiana, Colloidal Polymeric Nanoparticles and Brain Drug Delivery, Current Drug Delivery 2009; 6 (3) . https://dx.doi.org/10.2174/156720109788680912