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Current HIV Research

Editor-in-Chief

ISSN (Print): 1570-162X
ISSN (Online): 1873-4251

Mini-Review Article

Handgrip Strength and Clinical Evolution of People Living with HIV: A Mini Narrative Review

In Press, (this is not the final "Version of Record"). Available online 07 August, 2024
Author(s): Luiz Fernando Gouvêa-e-Silva*, Lorhoâne Eduarda Simão de Morais, Giovana de Souza Gonçalves, Morganna Alves Siqueira, Vitória Souza Lima, Ludimila Paula Vaz Cardoso and Eduardo Vignoto Fernandes
Published on: 07 August, 2024

DOI: 10.2174/011570162X306973240802104449

Price: $95

Abstract

HIV infection is a worldwide epidemic. Antiretroviral therapy allows people living with HIV (PLHIV) increased longevity and a better quality of life. Among the various ways of monitoring the clinical evolution of PLHIV, handgrip strength (HGS) is a promising strategy, as this test can be used to assess the health condition quickly and at a low cost. In this sense, the present study aims to describe, through a literature review, the relationship between HGS and the clinical evolution of PLHIV, especially with morbimortality. Initially, it is highlighted that aging, HIV infection, and excess body fat are related to the loss of HGS in PLHIV.

Furthermore, PLHIV is more likely to present cardiometabolic diseases that can be aggravated by reduced HGS. Thus, in people without positive HIV serology, low HGS indirectly, through the presence of risk factors or cardiometabolic diseases, or directly increases the chance of mortality. In conclusion, the lack of studies on this topic for PLHIV is highlighted, and more longitudinal studies, including control groups, are needed.


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