Advancements in the Transdermal Drug Delivery Systems Utilizing Microemulsion-based Gels

Title:Advancements in the Transdermal Drug Delivery Systems Utilizing Microemulsion-based Gels

Volume: 30

Author(s): Yongjian Song, Wei Chen, Yu Yin, Jiunian Li, Meng Wang, Yi Liu*Xiaoliang Ren*

Affiliation:

• School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China

• School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China

Abstract: Microemulsion gel, as a promising transdermal nanoparticle delivery system, addresses the limitations of microemulsions and enhances their performance in drug delivery and release. This article aims to discuss the advantages of microemulsion gel, including improved drug bioavailability, reduced drug irritation, enhanced drug penetration and skin adhesion, and increased antimicrobial properties. It explores the methods for selecting microemulsion formulations and the general processes of microemulsion preparation, as well as commonly used oil phases, surfactants, and co-surfactants. Additionally, the biomedical applications of microemulsion gel in treating conditions, such as acne and psoriasis, are also discussed. Overall, this article elucidates the significant potential of microemulsion gel in topical drug delivery, providing insights into future development and clinical applications.

Cite this article as:

Song Yongjian, Chen Wei, Yin Yu, Li Jiunian, Wang Meng, Liu Yi*, Ren Xiaoliang*, Advancements in the Transdermal Drug Delivery Systems Utilizing Microemulsion-based Gels, Current Pharmaceutical Design 2024; 30 () . https://dx.doi.org/10.2174/0113816128305190240718112945