Multi-stimuli-responsive Hydrogels for Therapeutic Systems: An Overview on
Emerging Materials, Devices, and Drugs

Hamid   Reza   Garshasbi; Sina      Soleymani; Seyed   Morteza   Naghib; M.R.      Mozafari

doi:10.2174/0113816128304924240527113111

Abstract

The rising interest in hydrogels nowadays is due to their usefulness in physiological conditions as multi-stimuli-responsive hydrogels. To reply to the prearranged stimuli, including chemical triggers, light, magnetic field, electric field, ionic strength, temperature, pH, and glucose levels, dual/multi-stimuli-sensitive gels/hydrogels display controllable variations in mechanical characteristics and swelling. Recent attention has focused on injectable hydrogel-based drug delivery systems (DDS) because of its promise to offer regulated, controlled, and targeted medication release to the tumor site. These technologies have great potential to improve treatment outcomes and lessen side effects from prolonged chemotherapy exposure.

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Current Pharmaceutical Design

Title:Multi-stimuli-responsive Hydrogels for Therapeutic Systems: An Overview on Emerging Materials, Devices, and Drugs

Volume: 30 Issue: 26

Author(s): Hamid Reza Garshasbi, Sina Soleymani, Seyed Morteza Naghib*M.R. Mozafari

Affiliation:

Nanotechnology Department, School of Advanced Technologies, Iran University of Science and Technology (IUST), Tehran 1684613114, Iran

Abstract: The rising interest in hydrogels nowadays is due to their usefulness in physiological conditions as multi-stimuli-responsive hydrogels. To reply to the prearranged stimuli, including chemical triggers, light, magnetic field, electric field, ionic strength, temperature, pH, and glucose levels, dual/multi-stimuli-sensitive gels/hydrogels display controllable variations in mechanical characteristics and swelling. Recent attention has focused on injectable hydrogel-based drug delivery systems (DDS) because of its promise to offer regulated, controlled, and targeted medication release to the tumor site. These technologies have great potential to improve treatment outcomes and lessen side effects from prolonged chemotherapy exposure.

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Garshasbi Reza Hamid, Soleymani Sina, Naghib Morteza Seyed*, Mozafari M.R., Multi-stimuli-responsive Hydrogels for Therapeutic Systems: An Overview on Emerging Materials, Devices, and Drugs, Current Pharmaceutical Design 2024; 30 (26) . https://dx.doi.org/10.2174/0113816128304924240527113111

DOI https://dx.doi.org/10.2174/0113816128304924240527113111	Print ISSN 1381-6128
Publisher Name Bentham Science Publisher	Online ISSN 1873-4286