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Current Chemical Biology

Editor-in-Chief

ISSN (Print): 2212-7968
ISSN (Online): 1872-3136

Research Article

Physico-chemical and Biological Investigations of Ocimum Basilicum L. Cultivated in Algeria

In Press, (this is not the final "Version of Record"). Available online 03 June, 2024
Author(s): S. Merzouki*, S. Boukeria, F. Louafi, M. Hakki Alma, R. Erenler, I. Yildiz, M. boulkroune and C. Mouats
Published on: 03 June, 2024

DOI: 10.2174/0122127968300108240527090556

Price: $95

Abstract

Introduction: This study aims to explore biologically active substances from natural sources, such as the Ocimum basilicum L. plant, for potential medicines. The LC-MS/MS analysis reveals that the majority of compounds in the aerial portion of this plant have Hesperidin and Vanillic acid, which are used in treating blood vessel fragility and neurological diseases (disorders) like Alzheimer's and Parkinson's.

Method: The study conducted a qualitative phytochemical screening of the hydromethanolic plant extract, revealing different secondary metabolites. Quantitative studies were conducted to determine the quantities of polyphenols, flavonoids, tannins, and alkaloids in the extract.

Results: Our investigations also assessed the antioxidant activity of the hydromethanolic plant extract using DPPH-free radical scavenging and cyclic voltammetry, providing insights into its potential to combat oxidative stress.

Conclusion: Finally, the anticoagulant activity of the hydromethanolic plant extract was examined through Quick and Cephaline Kaolin time coagulation exploration tests, providing insights into its impact on coagulation pathways.


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