Abstract
Introduction: This study aims to explore biologically active substances from natural sources, such as the Ocimum basilicum L. plant, for potential medicines. The LC-MS/MS analysis reveals that the majority of compounds in the aerial portion of this plant have Hesperidin and Vanillic acid, which are used in treating blood vessel fragility and neurological diseases (disorders) like Alzheimer's and Parkinson's.
Method: The study conducted a qualitative phytochemical screening of the hydromethanolic plant extract, revealing different secondary metabolites. Quantitative studies were conducted to determine the quantities of polyphenols, flavonoids, tannins, and alkaloids in the extract.
Results: Our investigations also assessed the antioxidant activity of the hydromethanolic plant extract using DPPH-free radical scavenging and cyclic voltammetry, providing insights into its potential to combat oxidative stress.
Conclusion: Finally, the anticoagulant activity of the hydromethanolic plant extract was examined through Quick and Cephaline Kaolin time coagulation exploration tests, providing insights into its impact on coagulation pathways.
Current Chemical Biology
Title:Physico-chemical and Biological Investigations of Ocimum Basilicum L. Cultivated in Algeria
Volume: 18
Author(s): Soraya Merzouki*, Sabah Boukeria, Fadila Louafi, Mohemet Hakki Alma, Ramazan Erenler, Ilyes Yildiz, Mina boulkroune and Chabane Mouats
Affiliation:
- Department of Process Engineering, Sciences and Technologies Institute, University Center Abdelhafidh Boussouf, Mila, 43000, Algeria
- Structural Molecular Environment Chemistry Research Unit (CHEMS) Constantine university 1, Constantine, 25000, Algeria
Abstract: Introduction: This study aims to explore biologically active substances from natural sources, such as the Ocimum basilicum L. plant, for potential medicines. The LC-MS/MS analysis reveals that the majority of compounds in the aerial portion of this plant have Hesperidin and Vanillic acid, which are used in treating blood vessel fragility and neurological diseases (disorders) like Alzheimer's and Parkinson's.
Method: The study conducted a qualitative phytochemical screening of the hydromethanolic plant extract, revealing different secondary metabolites. Quantitative studies were conducted to determine the quantities of polyphenols, flavonoids, tannins, and alkaloids in the extract.
Results: Our investigations also assessed the antioxidant activity of the hydromethanolic plant extract using DPPH-free radical scavenging and cyclic voltammetry, providing insights into its potential to combat oxidative stress.
Conclusion: Finally, the anticoagulant activity of the hydromethanolic plant extract was examined through Quick and Cephaline Kaolin time coagulation exploration tests, providing insights into its impact on coagulation pathways.
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Cite this article as:
Merzouki Soraya*, Boukeria Sabah, Louafi Fadila, Alma Hakki Mohemet, Erenler Ramazan, Yildiz Ilyes, boulkroune Mina and Mouats Chabane, Physico-chemical and Biological Investigations of Ocimum Basilicum L. Cultivated in Algeria, Current Chemical Biology 2024; 18 () . https://dx.doi.org/10.2174/0122127968300108240527090556
DOI https://dx.doi.org/10.2174/0122127968300108240527090556 |
Print ISSN 2212-7968 |
Publisher Name Bentham Science Publisher |
Online ISSN 1872-3136 |
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