Pyrazole Paradigms: Unveiling Synthetic Pathways and Unraveling Anti-Cancer Potential

Title:Pyrazole Paradigms: Unveiling Synthetic Pathways and Unraveling Anti-Cancer Potential

Volume: 20 Issue: 8

Author(s): Poonam Kumari, Neetu Agrawal*Somdutt Mujwar

Affiliation:

• Institute of Pharmaceutical Research, GLA University, Mathura-281406, UP, India

Abstract: This review investigates the synthetic methods and anti-cancer activities of pyrazole compounds. Various synthetic approaches, including traditional organic synthesis and microwaveassisted synthesis, have been used to change the pyrazole core structure, resulting in new compounds with improved pharmacological properties. The paper also covers the mechanisms of action that underpin pyrazole derivatives' anti-cancer characteristics, focusing on interactions with major molecular targets implicated in cancer growth and proliferation. SAR insights help to rationally develop novel anti-cancer drugs. In conclusion, the review emphasizes the versatility of pyrazole derivatives as scaffolds for the discovery and development of new anti-cancer medicines. By understanding synthesis routes and unravelling anti-cancer potential, this study hopes to encourage new research endeavours focused on leveraging the therapeutic advantages of pyrazole paradigms in the fight against cancer.

Cite this article as:

Kumari Poonam, Agrawal Neetu*, Mujwar Somdutt, Pyrazole Paradigms: Unveiling Synthetic Pathways and Unraveling Anti-Cancer Potential, Medicinal Chemistry 2024; 20 (8) . https://dx.doi.org/10.2174/0115734064312273240429110026