Nanoparticles as Drug Delivery Carrier-synthesis, Functionalization and Application

Title:Nanoparticles as Drug Delivery Carrier-synthesis, Functionalization and Application

Volume: 30

Author(s): S. Drishya, Ramakrishna Prasad Are, Prabhudutta Hota and Anju R. Babu*

Affiliation:

• Department of Biotechnology and Medical Engineering, National Institute of Technology Rourkela, Odisha, India

Abstract: In recent years, advancements in chemistry have allowed the tailoring of materials at the nanoscopic level as needed. There are mainly four main types of nanomaterials used as drug carriers:metal-based nanomaterials, organic nanomaterials, inorganic nanomaterials, and polymer nanomaterials. The nanomaterials as a drug carrier showed advantages for decreased side effects with a higher therapeutic index. The stability of the drug compounds is increased by encapsulation of the drug within the nano-drug carriers, leading to decreased systemic toxicity. Nano-drug carriers are also used for controlled drug release by tailoring system-made solubility characteristics of nanoparticles by surface coating with surfactants. The review focuses on the different types of nanoparticles used as drug carriers, the nanoparticle synthesis process, techniques of nanoparticle surface coating for drug carrier purposes, applications of nano-drug carriers, and prospects of nanomaterials as drug carriers for biomedical applications.

Cite this article as:

Drishya S., Are Ramakrishna Prasad, Hota Prabhudutta and Babu Anju R.*, Nanoparticles as Drug Delivery Carrier-synthesis, Functionalization and Application, Current Pharmaceutical Design 2024; 30 () . https://dx.doi.org/10.2174/0113816128304018240415095912