Smart Materials Design for Antibacterial Application

Title:Smart Materials Design for Antibacterial Application

Volume: 12

Author(s): Anurag Chaudhary, Neha Krishnarth, Prabash Tripathi, Amrendra Kumar Chaudhary, Chandrababu Rejeeth and Alok Sharma*

Affiliation:

• Department of Pharmaceutical Technology, Meerut Institute of Engineering and Technology, NH-58, Baghpat Road Crossing, Bypass Road, Meerut-250005, India

Abstract: In response to the escalating issue of antibiotic-resistant bacteria adhering to and thriving on medical equipment, scientists are pioneering innovative "intelligent" materials and coatings. These advancements entail the targeted release of antimicrobial substances, specifically activated when bacteria are detected. The next section discusses three revolutionary substances: hydrogels, nanoparticles, and thin films. Furthermore, intelligent antibacterial materials are divided into 2 groups based on the triggering source: those that react to biological stimuli and those that react to non-biological ones, like temperature and electric cues associated with bacterial presence, such as pH shifts or bacterial enzyme discharge. Moreover, because of their simple construction technique, outstanding biocompatibility, and robust antibacterial characteristics derived from polyphenols and metal ions, metallic-polyphenolic nanoparticles (MPNs) have obtained substantial interest in tackling antimicrobial infections. This article presents an introduction to several MPN-centered biomaterials (like nanoparticles, coatings, capsules, and hydrogels) and highlights the latest advancements in research in its applications for addressing microbial threats in the field of biomedicine. Furthermore, the usage of smart materials is classified based on their application domains, encompassing medical implants, waste reduction, and nano-engineered systems.

Cite this article as:

Chaudhary Anurag, Krishnarth Neha, Tripathi Prabash, Chaudhary Kumar Amrendra, Rejeeth Chandrababu and Sharma Alok*, Smart Materials Design for Antibacterial Application, Pharmaceutical Nanotechnology 2024; 12 () . https://dx.doi.org/10.2174/0122117385274576240209054652