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Current Drug Research Reviews

Editor-in-Chief

ISSN (Print): 2589-9775
ISSN (Online): 2589-9783

Review Article

Emulgel: A Cutting Edge Approach for Topical Drug Delivery System

In Press, (this is not the final "Version of Record"). Available online 31 January, 2024
Author(s): Anjali Jain, Prashant Kumar, Anurag Verma, Bibhash Chandra Mohanta, Sumel Ashique*, Radheshyam Pal, Shubneesh Kumar and Neeraj Mishra
Published on: 31 January, 2024

DOI: 10.2174/0125899775278612240129055753

Price: $95

Abstract

Emulgel is considered an advanced leading form of topical drug delivery system. It possesses the quality of a dual control drug mechanism for drug release as it holds the properties of both gel as well as emulsion. Emulgel is capable of overcoming the problems of the conventional route of topical drug delivery, like low spreadability and stickiness with the delivery of hydrophobic drugs, enhanced bioavailability at the local site of action, no greasy texture, and ensuring patient compliance. An emulsion is used either w/o or o/w, and the drug can be incorporated into the suitable phase of the emulsion. After that, the emulsion is incorporated into the gel phase. Several factors like oil phase, gelling agent, and emulsifier can affect the efficacy and stability. This advancement is beneficial not only for dermatology but also for cosmetology as well. Currently, emulgel-based formulations are used for the delivery of anti-inflammatory, analgesic, anti-acne, and antifungal drugs with a wide array of exploration.


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