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Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Review Article

1,3,4-Thiadiazole: A Versatile Scaffold for Drug Discovery

Author(s): Ravi K. Mittal*, Raghav Mishra, Vikram Sharma and Isha Mishra

Volume 21, Issue 5, 2024

Published on: 22 December, 2023

Page: [400 - 413] Pages: 14

DOI: 10.2174/0115701786274678231124101033

Price: $65

Abstract

1,3,4-Thiadiazole has garnered considerable attention in the scientific community due to its captivating molecular structure and ability to serve as a foundation for creating novel pharmaceutical compounds. Numerous medications feature the 1,3,4-thiadiazole ring in their chemical structure, highlighting its relevance and efficacy in pharmaceutical research and development. The key objective of this comprehensive review is to provide an understandable overview of the chemistry and diverse pharmacological activities associated with 1,3,4-thiadiazole compounds. The manuscript was compiled by conducting a thorough literature review, which included an in-depth analysis of globally esteemed scientific research databases. The remarkable chemical characteristics and diverse pharmacological impacts of 1,3,4-Thiadiazole highlight its significant potential as a structural scaffold for the development of novel therapeutic substances. Based on the information available on synthetic molecules that incorporate the 1,3,4-thiadiazole framework and their wide range of uses, it is reasonable to expect significant advancements in the near future and the possibility of employing these compounds in different domains.

Graphical Abstract

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