Login Register Cart 0
Generic placeholder image

Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Back
Journal Home About Journal Editorial Board Journal Insight Current Issue Volumes/Issues
Subscribe
Research Article

Phytochemical Evaluation of Selected Ayurvedic Formulations and Evaluate their Antioxidant Activity

Author(s): Awadhesh Kumar, Akash Ved, Karuna S. Shukla and Amit Kumar Nigam*

Volume 21, Issue 3, 2024

Published on: 27 November, 2023

Page: [279 - 301] Pages: 23

DOI: 10.2174/0115701786226175231023112257

Price: $65

Abstract

The Ayurvedic formulations' evaluation is very wide and deep. The project's goal was to evaluate the phytochemistry and antioxidant activity of Ayurvedic formulations used to treat digestive disorders. Herbal formulations are typically available as single or mixed formulations of multiple plant constituents, and it is critical to quantify the number of markers present in such formulations to ensure the product's high quality. The extract of formulations (Ajmodadi churna, Avipattikar churna, and Sanjivani vati) was subjected to physicochemical screening, phytochemical screening, HPTLC, and antioxidant activity was observed in the current study. Three ayurvedic formulations (Sanjivini vati, Ajmodadi Churna, and Avipattikar Churna) were studied physicochemically in this study. The extraction process determined the total phenolic and flavonoid content. The antioxidant capacity of the selected formulation was calculated by three methods; total antioxidant capacity, ferric- reducing power, and DPPH scavenging activity. The active constituent was isolated using the HPTLC method. This study shows that the formulations Ajmodai churna, Avipattikar churna, and Sanjivani vati are important sources of antioxidant compounds. The active constituent was isolated using the HPTLC method. The HPTLC technique showed the presence of phenolics and terpenoids that are responsible for antioxidant activity. Phenolics and Terpenoids, due to their antioxidant activity, are used as an important source for digestive disorders.

« Previous
Graphical Abstract

[1]
Aswatha Ram, H.N.; Sriwastava, N.K.; Shreedhara, C.S. Pharmacognosy Res., 2010, 2(2), 98-101.
[http://dx.doi.org/10.4103/0974-8490.62957] [PMID: 21808548]
[2]
Meena, A.K. Int. J. Pharmacogn. Phytochem, 2010, 2(1), 11-14.
[3]
Vaidya, A.D.B.; Devasagayam, T.P.A. J. Clin. Biochem. Nutr., 2007, 41(1), 1-11.
[http://dx.doi.org/10.3164/jcbn.2007001] [PMID: 18392106]
[4]
British Herbal Pharmacopoeia; British Herbal Medicine Association, 1996.
[5]
Sies, H. Exp. Physiol., 1997, 108(8)
[http://dx.doi.org/10.1113/expphysiol.1997.sp004024]
[6]
Sagar Bhanu, P.S.; Zafar, R.; Panwar, R. Indian Pharmacist, 2005, 4(35), 19-22.
[7]
Gautam, V.; Raman, R.M.V.; Ashish, K. Exporting Indian healthcare (Export potential of Ayurveda and Siddha products and services) Road beyond boundaries (The case of selected Indian healthcare systems); Gautam, V.; Raman, R.M.V.; Ashish, K., Eds.; Export-Import Bank of India: Mumbai, 2003, pp. 4-54.
[8]
Scott Raymond, P.W. Principles and Practice of Chromatography , 01-02.
[9]
Ayurvedic Formulary of India. Part I. Government of India- Ministry of Health and Family welfare; Department of Health, Controller of Publications: New Delhi, 1989, p. 154.
[10]
Amit, J.; Sunil, C.; Vimal, K.; Anupam, P. Pharm. Rev., 2007, 11, 13.
[11]
Anilakumar, K.R.; Saritha, V.; Khanum, F.; Bawa, A.S. Food Chem. Toxicol., 2009, 47(2), 279-282.
[http://dx.doi.org/10.1016/j.fct.2008.09.061] [PMID: 18940228]
[12]
Bhishagratna, G.D.; Bhaishajyaratnavali, In: J Nat Prod, 2003;, 19, pp. (1)3-8.
[13]
Charaka, S. Vidyotini hindi comm, 16th ed; , 1989.
[14]
Bjelakovic, G.; Nikolova, D.; Gluud, L.L.; Simonetti, R.G.; Gluud, C. JAMA, 2007, 297(8), 842-857.
[http://dx.doi.org/10.1001/jama.297.8.842] [PMID: 17327526]
[15]
German, J.B. Adv. Exp. Med. Biol., 1999, 459, 23-50.
[http://dx.doi.org/10.1007/978-1-4615-4853-9_3] [PMID: 10335367]
[16]
Jacob, R.A. Subcell. Biochem., 1996, 25, 1-16.
[http://dx.doi.org/10.1007/978-1-4613-0325-1_1] [PMID: 8821966]
[17]
Moreau, D. Reports of Sessions and. al; Memoirs of the Biological Society, 1922, pp. 86-321.
[18]
Wolf, G. J Nutr., 2005, 135(3), 363-366.
[19]
Yadav, N.P.; Dixit, V.K. Int. J. Integr. Biol., 2008, 2, 195-20.
[20]
Mattill, H.A. Annu. Rev. Biochem., 1947, 16(1), 177-192.
[http://dx.doi.org/10.1146/annurev.bi.16.070147.001141] [PMID: 20259061]
[21]
Chauhan, N.S. Medicinal and aromatic plants of Himachal Pradesh; Indus publishing company: New Delhi, 1995, p. 5.

Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy