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Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Research Article

Phytochemical Evaluation of Selected Ayurvedic Formulations and Evaluate their Antioxidant Activity

Author(s): Awadhesh Kumar, Akash Ved, Karuna S. Shukla and Amit Kumar Nigam*

Volume 21, Issue 3, 2024

Published on: 27 November, 2023

Page: [279 - 301] Pages: 23

DOI: 10.2174/0115701786226175231023112257

Price: $65

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Abstract

The Ayurvedic formulations' evaluation is very wide and deep. The project's goal was to evaluate the phytochemistry and antioxidant activity of Ayurvedic formulations used to treat digestive disorders. Herbal formulations are typically available as single or mixed formulations of multiple plant constituents, and it is critical to quantify the number of markers present in such formulations to ensure the product's high quality. The extract of formulations (Ajmodadi churna, Avipattikar churna, and Sanjivani vati) was subjected to physicochemical screening, phytochemical screening, HPTLC, and antioxidant activity was observed in the current study. Three ayurvedic formulations (Sanjivini vati, Ajmodadi Churna, and Avipattikar Churna) were studied physicochemically in this study. The extraction process determined the total phenolic and flavonoid content. The antioxidant capacity of the selected formulation was calculated by three methods; total antioxidant capacity, ferric- reducing power, and DPPH scavenging activity. The active constituent was isolated using the HPTLC method. This study shows that the formulations Ajmodai churna, Avipattikar churna, and Sanjivani vati are important sources of antioxidant compounds. The active constituent was isolated using the HPTLC method. The HPTLC technique showed the presence of phenolics and terpenoids that are responsible for antioxidant activity. Phenolics and Terpenoids, due to their antioxidant activity, are used as an important source for digestive disorders.

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