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ISSN (Print): 1874-6098
ISSN (Online): 1874-6128

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Review Article

The Relationship Between Sarcopenia And Proteinuria, What Do We Know?

Author(s): Ozkan Gungor, Sena Ulu, Ayca Inci*, Kenan Topal and Kamyar Kalantar-Zadeh

Volume 17, Issue 2, 2024

Published on: 15 November, 2023

Page: [93 - 102] Pages: 10

DOI: 10.2174/0118746098232969231106091204

Price: $65

Abstract

Sarcopenia is one of the most common geriatric syndromes in the elderly. It is defined as a decrease in muscle mass and function, and it can lead to physical disability, falls, poor quality of life, impaired immune system, and death. It is known that, the frequency of sarcopenia increases in the kidney patient population compared to healthy individuals. Although it is known that kidney disease can lead to sarcopenia; our knowledge of whether sarcopenia causes kidney disease is limited. Prior studies have suggested that protein energy wasting may be a risk of de novo CKD. Proteinuria is an important manifestation of kidney disease and there is a relationship between sarcopenia and proteinuria in diabetes, geriatric population, kidney transplant, and nephrotic syndrome. Does proteinuria cause sarcopenia or vice versa? Are they both the results of common mechanisms? This issue is not clearly known. In this review, we examined the relationship between sarcopenia and proteinuria in the light of other studies.

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Graphical Abstract

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