The Thyroid-cardiac Axis: Thyroid Function, Cardiac Rhythmology, and Sudden Cardiac Death

Title:The Thyroid-cardiac Axis: Thyroid Function, Cardiac Rhythmology, and Sudden Cardiac Death

Volume: 24 Issue: 10

Author(s): Michael Spartalis*, Eleftherios Spartalis, Stavroula A. Paschou, Dimitrios C. Iliopoulos and Gerasimos Siasos

Affiliation:

• 3rd Department of Cardiology, Sotiria Thoracic Diseases General Hospital, National and Kapodistrian University of Athens, Athens, Greece

Abstract: It is well known that thyroid dysfunction increases the risk of cardiovascular mortality and morbidity. The pleiotropic effect of thyroid hormones has a profound effect on the cardiovascular system, influencing both the formation of a normal cardiac rhythm and rhythm disturbance. A number of research studies have demonstrated correlations between TSH and FT4 levels and significant cardiovascular events. The pathophysiological mechanisms underlying these complex associations are, however, inadequately defined. A system-based examination of the relationship between thyroid homeostasis and cardiovascular disease could pave the way for novel study areas and a more individualised strategy for the management of individuals at cardiovascular risk.

Cite this article as:

Spartalis Michael*, Spartalis Eleftherios, Paschou Stavroula A., Iliopoulos C. Dimitrios and Siasos Gerasimos, The Thyroid-cardiac Axis: Thyroid Function, Cardiac Rhythmology, and Sudden Cardiac Death, Endocrine, Metabolic & Immune Disorders - Drug Targets 2024; 24 (10) . https://dx.doi.org/10.2174/0118715303243951231024112208