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Current Nanoscience

Editor-in-Chief

ISSN (Print): 1573-4137
ISSN (Online): 1875-6786

Review Article

A Review on Nano/Microfluidic Devices for Cell Isolation Techniques: Recent Progress and Advances

Author(s): Hamid Reza Garshasbi and Seyed Morteza Naghib*

Volume 20, Issue 6, 2024

Published on: 20 October, 2023

Page: [717 - 739] Pages: 23

DOI: 10.2174/0115734137264742231001142853

Price: $65

Abstract

Micro/nanofluidic devices and systems have gained increasing interest in healthcare applications over the last few decades because of their low cost and ease of customization, with only a small volume of sample fluid required. Many biological queries are now being addressed using various types of single-molecule research. With this rapid rise, the disadvantages of these methods are also becoming obvious. Micro/nanofluidics-based biochemical analysis outperforms traditional approaches in terms of sample volume, turnaround time, ease of operation, and processing efficiency. A complex and multifunctional micro/nanofluidic platform may be used for single-cell manipulation, treatment, detection, and sequencing. We present an overview of the current advances in micro/nanofluidic technology for single-cell research, focusing on cell capture, treatment, and biochemical analyses. The promise of single-cell analysis using micro/ nanofluidics is also highlighted.

Graphical Abstract

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