Introduction to a New Technique in Organic Synthesis: Recent Advances in Aqueous Reactions of Sparingly Soluble High-Melting Point Substrates Promoted by Granular Polytetrafluoroethylene

Title:Introduction to a New Technique in Organic Synthesis: Recent Advances in Aqueous Reactions of Sparingly Soluble High-Melting Point Substrates Promoted by Granular Polytetrafluoroethylene

Volume: 21

Author(s): Linlin Xing*, Yong Zhang, Taixuan Jia and Chunbao Li

Affiliation:

• Anyang Institute of Technology School of Chemistry and Environmental Engineering Anyang China

Abstract: Water, a kind of abundant natural resource, is considered to be a green and desirable solvent for reasons of its low cost, high safety and environmental friendliness. This review article aims to briefly introduce the methodologies that have utilized water as reaction media under the aid of granular polytetrafluoroethylene (PTFE) to mediate reactions of a series of water-insoluble and high melting points substrates in a green, quantitative, fast, and stereoselective way in most situations. Besides, this review will be helpful to stimulate further study on both practical applications and mechanistic understanding of these aqueous reactions promoted by granular PTFE for the novel synthesis of interesting structures.

Cite this article as:

Xing Linlin*, Zhang Yong, Jia Taixuan and Li Chunbao, Introduction to a New Technique in Organic Synthesis: Recent Advances in Aqueous Reactions of Sparingly Soluble High-Melting Point Substrates Promoted by Granular Polytetrafluoroethylene, Mini-Reviews in Organic Chemistry 2024; 21 () . https://dx.doi.org/10.2174/0118756298253318230929034500