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Current Drug Research Reviews

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ISSN (Print): 2589-9775
ISSN (Online): 2589-9783

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Review Article

Therapeutic and Phytochemical Properties of Thymoquinone Derived from Nigella sativa

Author(s): Gaurav Tiwari, Monisha Gupta, Lalchand D. Devhare and Ruchi Tiwari*

Volume 16, Issue 2, 2024

Published on: 24 August, 2023

Page: [145 - 156] Pages: 12

DOI: 10.2174/2589977515666230811092410

Price: $65

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Abstract

Background: Nigella sativa (N. sativa), commonly known as black seed or black cumin, belongs to the family Ranunculaceae. It contains several phytoconstituents, Thymoquinone (TQ), thymol, thymohydroquinone, carvacrol, and dithymoquinone. TQ is the main phytoconstituent present in N. sativa that is used as an herbal compound, and it is widely used as an antihypertensive, liver tonic, diuretic, digestive, anti-diarrheal, appetite stimulant, analgesic, and antibacterial agent, and in skin disorders.

Objective: The study focused on collecting data on the therapeutic or pharmacological activities of TQ present in N. sativa seed.

Methods: Antidiabetic, anticancer, immunomodulator, analgesic, antimicrobial, anti-inflammatory, hepato-protective, renal protective, and antioxidant properties of TQ have been studied by various scientists.

Conclusion: TQ seems to have a variety of consequences on how infected cells behave at the cellular level.

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Graphical Abstract

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