Advances in Enzyme-responsive Supramolecular In situ Self-assembled Peptide for Drug Delivery

Wentao      Xu; Xiaowen      Qin; Yang      Liu; Jun      Chen; Yuguang      Wang

doi:10.2174/1567201820666230726151607

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Abstract

Because of low immunogenicity, ease of modification, and inherent biosafety, peptides have been well recognized as vehicles to deliver therapeutic agents to targeted regions with improved pharmacokinetic characteristics. Enzyme-responsive self-assembled peptides (ERSAPs) show superiority over their naive forms due to their enhanced targeting efficacy and long-retention property. In this review, we have summarized recent advances in the therapeutic application of ERSAPs, mainly focusing on their self-therapeutic properties and potential as vehicles to deliver different drugs.

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DOI https://dx.doi.org/10.2174/1567201820666230726151607	Print ISSN 1567-2018
Publisher Name Bentham Science Publisher	Online ISSN 1875-5704

Current Drug Delivery

Advances in Enzyme-responsive Supramolecular In situ Self-assembled Peptide for Drug Delivery

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