Abstract
Resveratrol is a stilbene class of phenolic phytochemical that has a wide range of utilization in several industries, including pharmaceutical, food and cosmetic industries. It is available in several plants, including grapes, berries, and peanuts. Major focus of research regarding resveratrol has been its therapeutic potential against major diseases, including cardiovascular, inflammatory, cancer, microbial and age-related diseases. However, its extraction methods have not been of much discussion. In this review, nonconventional methods, including supercritical fluid extraction, subcritical water extraction, microwave- assisted extraction, ultrasound assisted extraction, and high hydrostatic pressure extraction have been discussed in contrast to widely implemented conventional extraction methods. Nonconventional methods are considerably advanced over conventional methods. In this review, the efficiency of various nonconventional methods via optimization of their extraction parameters, such as the effects of modifiers, solvents, pressure, temperature, and extraction time, have been evaluated. Improvised extraction methods may result in cost-effective isolation of resveratrol.
Graphical Abstract
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