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ISSN (Print): 1389-2010
ISSN (Online): 1873-4316

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Review Article

Lithium and Microorganisms: Biological Effects and Mechanisms

Author(s): Evgenii Plotnikov*, Dariya Pukhnyarskaya and Anna Chernova

Volume 24, Issue 13, 2023

Published on: 22 March, 2023

Page: [1623 - 1629] Pages: 7

DOI: 10.2174/1389201024666230302153849

Price: $65

Abstract

This review covers the lithium effects on microorganisms, including gut and soil bacteria. Available studies of the biological effects of lithium salts have revealed a wide range of different effects of lithium cations on various microorganisms, but so far, the study of this direction has not been summarized enough. Here we consider the confirmed and various plausible mechanisms of lithium action on microorganisms. Special emphasis is placed on assessing the effect of lithium ions under oxidative stress and adverse environmental conditions. The impact of lithium on the human microbiome is also being reviewed and discussed. Controversial effects of lithium have been shown, including the inhibitory and stimulating effects of lithium on bacterial growth.

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