Login Register Cart 0
Generic placeholder image

Current Analytical Chemistry

Editor-in-Chief

ISSN (Print): 1573-4110
ISSN (Online): 1875-6727

Back
Journal Home About Journal Editorial Board Journal Insight Current Issue Volumes/Issues
Subscribe
Review Article

Analytical Methods for the Determination of Atypical Antipsychotic Drugs - An Update

Author(s): Vasanti Suvarna* and Adishri Raut

Volume 19, Issue 2, 2023

Published on: 27 December, 2022

Page: [147 - 175] Pages: 29

DOI: 10.2174/1573411019666221124091026

Price: $65

Abstract

Atypical antipsychotics have gained incredible attention over the last decade and are widely prescribed for short-term and chronic treatment of various psychopathological diseases, including schizophrenia, mania, delirium, bipolar disorder, depression, autism spectrum disorder, and affective disorders. Due to their better clinical profile and therapeutic benefits, atypical antipsychotics have become a better choice for psychopathological treatment and management. However, their usage is associated with peripheral side effects and metabolic diseases impacting the quality of life of patients. In the sight of these circumstances, strategic development of analytical methods to isolate atypical antipsychotics from a variety of formulations and biological samples and identify and quantify them with great sensitivity and accuracy is of great importance in clinical and forensic settings. In the present review, we have summarized and discussed various analytical methods reported in the literature over the last decade in various formulations and biological samples, highlighting analytical trends to the analysts in the field of atypical antipsychotics.

« Previous Next »
Graphical Abstract

[1]
Tamminga, C.A.; Lahti, A.C. Treatments for chronic psychosis. Dialogues Clin. Neurosci., 2001, 3(4), 281-292.
[http://dx.doi.org/10.31887/DCNS.2001.3.4/ctamminga] [PMID: 22033485]
[2]
Bortolozzi, A.; Díaz-Mataix, L.; Toth, M.; Celada, P.; Artigas, F. In vivo actions of aripiprazole on serotonergic and dopaminergic systems in rodent brain. Psychopharmacology (Berl.), 2007, 191(3), 745-758.
[http://dx.doi.org/10.1007/s00213-007-0698-y] [PMID: 17265076]
[3]
Auclair, A.L.; Kleven, M.S.; Besnard, J.; Depoortère, R.; Newman-Tancredi, A. Actions of novel antipsychotic agents on apomorphine-induced PPI disruption: Influence of combined serotonin 5-HT1A receptor activation and dopamine D2 receptor blockade. Neuropsychopharmacology, 2006, 31(9), 1900-1909.
[http://dx.doi.org/10.1038/sj.npp.1301015] [PMID: 16421514]
[4]
Gajwani, P.; Kemp, D.E.; Muzina, D.J.; Xia, G.; Gao, K.; Calabrese, J.R. Acute treatment of mania: An update on new medications. Curr. Psychiatry Rep., 2006, 8(6), 504-509.
[http://dx.doi.org/10.1007/s11920-006-0058-3] [PMID: 17094930]
[5]
Chengappa, K.N.; Suppes, T.; Berk, M. Treatment of bipolar mania with atypical antipsychotics. Expert Rev. Neurother., 2004, 4(6)(Suppl. 2), S17-S25.
[http://dx.doi.org/10.1586/14737175.4.6.S17] [PMID: 16279862]
[6]
Curran, M.P.; Perry, C.M. Amisulpride: A review of its use in the management of schizophrenia. Drugs, 2001, 61(14), 2123-2150.
[http://dx.doi.org/10.2165/00003495-200161140-00014] [PMID: 11735643]
[7]
Meltzer, H.Y.; Dritselis, A.; Yasothan, U.; Kirkpatrick, P. Asenapine. Nat. Rev. Drug Discov., 2009, 8(11), 843-844.
[http://dx.doi.org/10.1038/nrd3027] [PMID: 19876039]
[8]
Tenjin, T.; Miyamoto, S.; Ninomiya, Y.; Kitajima, R.; Ogino, S.; Miyake, N.; Yamaguchi, N. Profile of blonanserin for the treatment of schizophrenia. Neuropsychiatr. Dis. Treat., 2013, 9, 587-594.
[http://dx.doi.org/10.2147/NDT.S34433] [PMID: 23766647]
[9]
Campbell, R.H.; Diduch, M.; Gardner, K.N.; Thomas, C. Review of cariprazine in management of psychiatric illness. Ment. Health Clin., 2018, 7(5), 221-229.
[http://dx.doi.org/10.9740/mhc.2017.09.221] [PMID: 29955527]
[10]
Velasco, A.; Lérida, M.T.; Mayo, R.; Pérez-Accino, C.; Alamo, C. Comparative study of the effects of clozapine and clothiapine in different preparations of guinea pig and rat isolated organs. Gen. Pharmacol., 1998, 30(4), 521-524.
[http://dx.doi.org/10.1016/S0306-3623(97)00297-8] [PMID: 9522169]
[11]
Stępnicki, P.; Kondej, M.; Kaczor, A.A. Current concepts and treatments of schizophrenia. Molecules, 2018, 23(8), 2087.
[http://dx.doi.org/10.3390/molecules23082087] [PMID: 30127324]
[12]
Bhana, N.; Foster, R.H.; Olney, R.; Plosker, G.L. Olanzapine: An updated review of its use in the management of schizophrenia. Drugs, 2001, 61(1), 111-161.
[http://dx.doi.org/10.2165/00003495-200161010-00011] [PMID: 11217867]
[13]
Gilday, E.; Nasrallah, H.A. Clinical pharmacology of paliperidone palmitate a parenteral long-acting formulation for the treatment of schizophrenia. Rev. Recent Clin. Trials, 2012, 7(1), 2-9.
[http://dx.doi.org/10.2174/157488712799363307] [PMID: 22023179]
[14]
Jann, M.W.; Penzak, S.R. Correction to: Long-acting injectable second-generation antipsychotics: An update and comparison between agents. CNS Drugs, 2018, 32(6), 603-603.
[http://dx.doi.org/10.1007/s40263-018-0531-7] [PMID: 29858836]
[15]
Shrivastava, A.; Johnston, M.E. Weight-gain in psychiatric treatment: Risks, implications, and strategies for prevention and management. Mens Sana Monogr., 2010, 8(1), 53-68.
[http://dx.doi.org/10.4103/0973-1229.58819] [PMID: 21327170]
[16]
Cao, Y.; Zhao, F.; Chen, J.; Huang, T.; Zeng, J.; Wang, L.; Sun, X.; Miao, Y.; Wang, S.; Chen, C. A simple and rapid LC-MS/MS method for the simultaneous determination of eight antipsychotics in human serum, and its application to therapeutic drug monitoring. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2020, 1147, 122129.
[http://dx.doi.org/10.1016/j.jchromb.2020.122129] [PMID: 32416590]
[17]
Ansermot, N.; Brawand-Amey, M.; Kottelat, A.; Eap, C.B. Fast quantification of ten psychotropic drugs and metabolites in human plasma by ultra-high performance liquid chromatography tandem mass spectrometry for therapeutic drug monitoring. J. Chromatogr. A, 2013, 1292, 160-172.
[http://dx.doi.org/10.1016/j.chroma.2012.12.071] [PMID: 23380367]
[18]
Gradinaru, J.; Vullioud, A.; Eap, C.B.; Ansermot, N. Quantification of typical antipsychotics in human plasma by ultra-high performance liquid chromatography tandem mass spectrometry for therapeutic drug monitoring. J. Pharm. Biomed. Anal., 2014, 88, 36-44.
[http://dx.doi.org/10.1016/j.jpba.2013.07.041] [PMID: 24036032]
[19]
Domingues, D.S.; Souza, I.D.; Queiroz, M.E.C. Analysis of drugs in plasma samples from schizophrenic patients by column-switching liquid chromatography-tandem mass spectrometry with organic-inorganic hybrid cyanopropyl monolithic column. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2015, 993-994, 26-35.
[http://dx.doi.org/10.1016/j.jchromb.2015.04.040] [PMID: 25984963]
[20]
Koller, D.; Zubiaur, P.; Saiz-Rodríguez, M.; Abad-Santos, F.; Wojnicz, A. Simultaneous determination of six antipsychotics, two of their metabolites and caffeine in human plasma by LC-MS/MS using a phospholipid-removal microelution-solid phase extraction method for sample preparation. Talanta, 2019, 198, 159-168.
[http://dx.doi.org/10.1016/j.talanta.2019.01.112] [PMID: 30876545]
[21]
Kirchherr, H.; Kühn-Velten, W.N. Quantitative determination of forty-eight antidepressants and antipsychotics in human serum by HPLC tandem mass spectrometry: A multi-level, single-sample approach. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2006, 843(1), 100-113.
[http://dx.doi.org/10.1016/j.jchromb.2006.05.031] [PMID: 16798119]
[22]
Uřinovská, R.; Brozmanová, H.; Sištík, P.; Silhán, P.; Kacířová, I.; Lemr, K.; Grundmann, M. Liquid chromatography-tandem mass spectrometry method for determination of five antidepressants and four atypical antipsychotics and their main metabolites in human serum. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2012, 907, 101-107.
[http://dx.doi.org/10.1016/j.jchromb.2012.09.009] [PMID: 23026228]
[23]
Aravagiri, M.; Marder, S.R. Simultaneous determination of clozapine and its N-desmethyl and N-oxide metabolites in plasma by liquid chromatography/electrospray tandem mass spectrometry and its application to plasma level monitoring in schizophrenic patients. J. Pharm. Biomed. Anal., 2001, 26(2), 301-311.
[http://dx.doi.org/10.1016/S0731-7085(01)00410-1] [PMID: 11470207]
[24]
Aravagiri, M.; Marder, S.R.; Pollock, B. Determination of ziprasidone in human plasma by liquid chromatography-electrospray tandem mass spectrometry and its application to plasma level determination in schizophrenia patients. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2007, 847(2), 237-244.
[http://dx.doi.org/10.1016/j.jchromb.2006.10.024] [PMID: 17098485]
[25]
Mannocchi, G.; Pantano, F.; Tittarelli, R.; Catanese, M.; Umani Ronchi, F.; Busardò, F.P. Development and validation of a GC-MS method for the detection and quantification of clotiapine in blood and urine specimens and application to a postmortem case. Int. J. Anal. Chem., 2015, 2015, 972480.
[http://dx.doi.org/10.1155/2015/972480] [PMID: 26236337]
[26]
Avenoso, A.; Facciolà, G.; Campo, G.M.; Fazio, A.; Spina, E. Determination of clozapine, desmethylclozapine and clozapine N-oxide in human plasma by reversed-phase high-performance liquid chromatography with ultraviolet detection. J. Chromatogr. B Biomed. Sci. Appl., 1998, 714(2), 299-308.
[http://dx.doi.org/10.1016/S0378-4347(98)00202-3] [PMID: 9766870]
[27]
Canal-Raffin, M.; Déridet, E.; Titier, K.; Frakra, E.; Molimard, M.; Moore, N. Simplified ultraviolet liquid chromatographic method for determination of sertindole, dehydrosertindole and norsertindole, in human plasma. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2005, 814(1), 61-67.
[http://dx.doi.org/10.1016/j.jchromb.2004.10.020] [PMID: 15607708]
[28]
Llerena, A.; Berecz, R.; Norberto, M.J.; de la Rubia, A. Determination of clozapine and its N-desmethyl metabolite by high-performance liquid chromatography with ultraviolet detection. J. Chromatogr. B Biomed. Sci. Appl., 2001, 755(1-2), 349-354.
[http://dx.doi.org/10.1016/S0378-4347(01)00056-1] [PMID: 11393724]
[29]
Boulton, D.W.; Markowitz, J.S.; DeVane, C.L. A high-performance liquid chromatography assay with ultraviolet detection for olanzapine in human plasma and urine. J. Chromatogr. B Biomed. Sci. Appl., 2001, 759(2), 319-323.
[http://dx.doi.org/10.1016/S0378-4347(01)00240-7] [PMID: 11499485]
[30]
Olesen, O.V.; Linnet, K. Determination of olanzapine in serum by high-performance liquid chromatography using ultraviolet detection considering the easy oxidability of the compound and the presence of other psychotropic drugs. J. Chromatogr. B Biomed. Sci. Appl., 1998, 714(2), 309-315.
[http://dx.doi.org/10.1016/S0378-4347(98)00205-9] [PMID: 9766871]
[31]
Péhourcq, F.; Ouariki, S.; Bégaud, B. Rapid high-performance liquid chromatographic measurement of amisulpride in human plasma: Application to manage acute intoxication. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2003, 789(1), 101-105.
[http://dx.doi.org/10.1016/S1570-0232(03)00045-X] [PMID: 12726848]
[32]
Fisher, D.S.; Partridge, S.J.; Handley, S.A.; Couchman, L.; Morgan, P.E.; Flanagan, R.J. LC-MS/MS of some atypical antipsychotics in human plasma, serum, oral fluid and haemolysed whole blood. Forensic Sci. Int., 2013, 229(1-3), 145-150.
[http://dx.doi.org/10.1016/j.forsciint.2013.02.010] [PMID: 23477803]
[33]
Gschwend, M.H.; Arnold, P.; Ring, J.; Martin, W. Selective and sensitive determination of amisulpride in human plasma by liquid chromatography-tandem mass spectrometry with positive electrospray ionisation and multiple reaction monitoring. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2006, 831(1-2), 132-139.
[http://dx.doi.org/10.1016/j.jchromb.2005.11.042] [PMID: 16386474]
[34]
Lin, S.N.; Chang, Y.; Moody, D.E.; Foltz, R.L. A liquid chromatographic-electrospray-tandem mass spectrometric method for quantitation of quetiapine in human plasma and liver microsomes: Application to study in vitro metabolism. J. Anal. Toxicol., 2004, 28(6), 443-448.
[http://dx.doi.org/10.1093/jat/28.6.443] [PMID: 15516294]
[35]
Mészáros, G.P.; Ágai-Csongor, E.; Kapás, M. Sensitive LC-MS/MS methods for the quantification of RGH-188 and its active metabolites, desmethyl- and didesmethyl-RGH-188 in human plasma and urine. J. Pharm. Biomed. Anal., 2008, 48(2), 388-397.
[http://dx.doi.org/10.1016/j.jpba.2007.12.016] [PMID: 18242914]
[36]
Mosier, K.E.; Song, J.; McKay, G.; Hubbard, J.W.; Fang, J. Determination of clozapine, and its metabolites, N-desmethylclozapine and clozapine N-oxide in dog plasma using high-performance liquid chromatography. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2003, 783(2), 377-382.
[http://dx.doi.org/10.1016/S1570-0232(02)00655-4] [PMID: 12482480]
[37]
Nirogi, R.V.S.; Kandikere, V.N.; Shukla, M.; Mudigonda, K.; Maurya, S.; Boosi, R.; Yerramilli, A. Development and validation of a sensitive liquid chromatography/electrospray tandem mass spectrometry assay for the quantification of olanzapine in human plasma. J. Pharm. Biomed. Anal., 2006, 41(3), 935-942.
[http://dx.doi.org/10.1016/j.jpba.2006.01.040] [PMID: 16504450]
[38]
Patteet, L.; Maudens, K.E.; Sabbe, B.; Morrens, M.; De Doncker, M.; Neels, H. High throughput identification and quantification of 16 antipsychotics and 8 major metabolites in serum using ultra-high performance liquid chromatography-tandem mass spectrometry. Clin. Chim. Acta, 2014, 429, 51-58.
[http://dx.doi.org/10.1016/j.cca.2013.11.024] [PMID: 24291056]
[39]
Suckow, R.F.; Fein, M.; Correll, C.U.; Cooper, T.B. Determination of plasma ziprasidone using liquid chromatography with fluorescence detection. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2004, 799(2), 201-208.
[http://dx.doi.org/10.1016/j.jchromb.2003.10.027] [PMID: 14670738]
[40]
Ulrich, S.; Meyer, F.P.; Bogerts, B. A capillary gas-liquid chromatographic method for the assay of the neuroleptic drug zotepine in human serum or plasma. J. Pharm. Biomed. Anal., 1996, 14(4), 441-449.
[http://dx.doi.org/10.1016/0731-7085(95)01637-6] [PMID: 8729643]
[41]
Alcantara, G.K.S.; Calixto, L.A.; Rocha, B.A.; Júnior, F.B.; de Oliveira, A.R.M.; de Gaitani, C.M. A fast DLLME-LC-MS/MS method for risperidone and its metabolite 9-hydroxyrisperidone determination in plasma samples for therapeutic drug monitoring of patients. Microchem. J., 2020, 156, 104894.
[http://dx.doi.org/10.1016/j.microc.2020.104894]
[42]
Bhaitacharyya, S.; Rana, D.; Bhattacharyya, S.N. Determination of heat of formation of associated systems by calorimetry., 1997.
[http://dx.doi.org/10.5281/ZENODO.5875144]
[43]
Bhaitacharyya, S.; Rana, D.; Bhattacharyya, S.N. A thermodynamic study of molecular association by gas-liquid chromatography., 1997.
[http://dx.doi.org/10.5281/ZENODO.5880620]
[44]
Bhaitacharyya, S.; Rana, D.; Bhattacharyya, S.N. A thermodynamic study of molecular association by gas-liquid chromatography: Trilaurylaminealcohol systems 1997.
[http://dx.doi.org/10.5281/ZENODO.5901630]
[45]
Akamine, Y.; Yasui-Furukori, N.; Kojima, M.; Inoue, Y.; Uno, T. A sensitive column-switching HPLC method for aripiprazole and dehydroaripiprazole and its application to human pharmacokinetic studies. J. Sep. Sci., 2010, 33(21), 3292-3298.
[http://dx.doi.org/10.1002/jssc.201000457] [PMID: 21049519]
[46]
Musenga, A.; Saracino, M.A.; Spinelli, D.; Rizzato, E.; Boncompagni, G.; Kenndler, E.; Raggi, M.A. Analysis of the recent antipsychotic aripiprazole in human plasma by capillary electrophoresis and high-performance liquid chromatography with diode array detection. Anal. Chim. Acta, 2008, 612(2), 204-211.
[http://dx.doi.org/10.1016/j.aca.2008.02.046] [PMID: 18358867]
[47]
Jann, M.W. Short communication determination of clozapine and desmethylclozapine human plasma by high-performance liquid chromatography with ultraviolet detection in., 1992.
[48]
Lovdahl, M.; Perry, P.; Miller, D. The assay of clozapine and N-desmethylclozapine in human plasma by high-performance liquid chromatography. Ther. Drug Monit., 1991.
[49]
Mercolini, L.; Bugamelli, F.; Kenndler, E.; Boncompagni, G.; Franchini, L.; Raggi, M.A. Simultaneous determination of the antipsychotic drugs levomepromazine and clozapine and their main metabolites in human plasma by a HPLC-UV method with solid-phase extraction. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2007, 846(1-2), 273-280.
[http://dx.doi.org/10.1016/j.jchromb.2006.09.019] [PMID: 17045854]
[50]
Weigmann, H.; Hiemke, C. Determination of clozapine and its major metabolites in human serum using automated solid-phase extraction and subsequent isocratic high-performance liquid chromatography with ultraviolet detection. J. Chromatogr. B Biomed. Sci. Appl., 1992, 583(2), 209-216.
[http://dx.doi.org/10.1016/0378-4347(92)80554-4] [PMID: 1478985]
[51]
Sachse, J.; Härtter, S.; Weigmann, H.; Hiemke, C. Automated determination of amisulpride by liquid chromatography with column switching and spectrophotometric detection. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2003, 784(2), 405-410.
[http://dx.doi.org/10.1016/S1570-0232(02)00808-5] [PMID: 12505788]
[52]
Palego, L.; Dell’Osso, L.; Marazziti, D.; Biondi, L.; Sarno, N.; Ciapparelli, A.; Giromella, A.; Giannaccini, G.; Lucacchini, A.; Cassano, G.B. Simultaneous analysis of clozapine, clomipramine and their metabolites by reversed-phase liquid chromatography. Prog. Neuropsychopharmacol. Biol. Psychiatry, 2001, 25(3), 519-533.
[http://dx.doi.org/10.1016/S0278-5846(00)00184-6] [PMID: 11370995]
[53]
Shen, Y.L.; Wu, H.L.; Ko, W.K.; Wu, S.M. Simultaneous determination of clozapine, clozapine N-oxide, N-desmethylclozapine, risperidone, and 9-hydroxyrisperidone in plasma by high performance liquid chromatography with ultraviolet detection. Anal. Chim. Acta, 2002, 460, 201-208.
[http://dx.doi.org/10.1016/S0003-2670(02)00239-8]
[54]
Gonçalves, J.L.; Alves, V.L.; Conceição, C.J.F.; Teixeira, H.M.; Câmara, J.S. Development of MEPS-UHPLC/PDA methodology for the quantification of clozapine, risperidone and their major active metabolites in human urine. Microchem. J., 2015, 123, 90-98.
[http://dx.doi.org/10.1016/j.microc.2015.05.016]
[55]
Saracino, M.A.; Mercolini, L.; Flotta, G.; Albers, L.J.; Merli, R.; Raggi, M.A. Simultaneous determination of fluvoxamine isomers and quetiapine in human plasma by means of high-performance liquid chromatography. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2006, 843(2), 227-233.
[http://dx.doi.org/10.1016/j.jchromb.2006.06.001] [PMID: 16798118]
[56]
Mandrioli, R.; Fanali, S.; Ferranti, A.; Raggi, M.A. HPLC analysis of the novel antipsychotic drug quetiapine in human plasma. J. Pharm. Biomed. Anal., 2002, 30(4), 969-977.
[http://dx.doi.org/10.1016/S0731-7085(02)00395-3] [PMID: 12408887]
[57]
Mandrioli, R.; Mercolini, L.; Lateana, D.; Boncompagni, G.; Raggi, M.A. Analysis of risperidone and 9-hydroxyrisperidone in human plasma, urine and saliva by MEPS-LC-UV. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2011, 879(2), 167-173.
[http://dx.doi.org/10.1016/j.jchromb.2010.11.033] [PMID: 21183412]
[58]
Rao, D.; Pradesh, A.; Pradesh, A. Novel spectrophotometric methods for the determination of amisulpride in pure and pharmaceutical formulations. Int. J. Recent Sci. Res., 2015, 6, 4830-4837.
[59]
Kovatsi, L.; Titopoulou, A.; Tsakalof, A.; Samanidou, V. HPLC analysis of antipsychotic asenapine in alternative biomatrices: Hair and nail clippings. J. Liq. Chromatogr. Relat. Technol., 2015, 38, 1666-1670.
[http://dx.doi.org/10.1080/10826076.2015.1089894]
[60]
Dziurkowska, E.; Jiménez-Morigosa, C.; López-Rivadulla, M.; Wesolowski, M. Development and validation of solid-phase extraction coupled with a liquid chromatography-tandem mass spectrometry method for quantitation of olanzapine in saliva. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2020, 1136, 121896.
[http://dx.doi.org/10.1016/j.jchromb.2019.121896] [PMID: 31830662]
[61]
Huang, H.C.; Liu, C.H.; Lan, T.H.; Hu, T.M.; Chiu, H.J.; Wu, Y.C.; Tseng, Y.L. Detection and quantification of aripiprazole and its metabolite, dehydroaripiprazole, by gas chromatography-mass spectrometry in blood samples of psychiatric patients. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2007, 856(1-2), 57-61.
[http://dx.doi.org/10.1016/j.jchromb.2007.05.026] [PMID: 17602901]
[62]
Locatelli, I.; Mrhar, A.; Grabnar, I. Simultaneous determination of risperidone and 9-hydroxyrisperidone enantiomers in human blood plasma by liquid chromatography with electrochemical detection. J. Pharm. Biomed. Anal., 2009, 50(5), 905-910.
[http://dx.doi.org/10.1016/j.jpba.2009.06.013] [PMID: 19589654]
[63]
Josefsson, M.; Roman, M.; Skogh, E.; Dahl, M.L. Liquid chromatography/tandem mass spectrometry method for determination of olanzapine and N-desmethylolanzapine in human serum and cerebrospinal fluid. J. Pharm. Biomed. Anal., 2010, 53(3), 576-582.
[http://dx.doi.org/10.1016/j.jpba.2010.03.040] [PMID: 20452161]
[64]
Noh, K.; Jang, Y-J.; Kwon, K.I.; Kim, E.; Jeong, T.C.; Yun, H.Y.; Kang, W. Quantitative determination of amisulpride in rat plasma by HPLC-MS/MS. Arch. Pharm. Res., 2015, 38(1), 63-67.
[http://dx.doi.org/10.1007/s12272-014-0361-1] [PMID: 24619919]
[65]
Zhang, G.; Terry, A.V., Jr; Bartlett, M.G. Sensitive liquid chromatography/tandem mass spectrometry method for the simultaneous determination of olanzapine, risperidone, 9-hydroxyrisperidone, clozapine, haloperidol and ziprasidone in rat brain tissue. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2007, 858(1-2), 276-281.
[http://dx.doi.org/10.1016/j.jchromb.2007.08.007] [PMID: 17766202]
[66]
Ma, N.; Liu, W.Y.; Li, H.D.; Zhu, Y.G.; Zhang, B.K.; Wang, F.; Zhu, R.H.; Xiang, D.X. Determination of perospirone by liquid chromatography/electrospray mass spectrometry: Application to a pharmacokinetic study in healthy Chinese volunteers. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2007, 847(2), 210-216.
[http://dx.doi.org/10.1016/j.jchromb.2006.10.007] [PMID: 17116433]
[67]
Trawiński, J.; Skibiński, R. Photodegradation study of sertindole by UHPLC-ESI-Q-TOF and influence of some metal oxide excipients on the degradation process. Pharmaceutics, 2019, 11(7), E299.
[http://dx.doi.org/10.3390/pharmaceutics11070299] [PMID: 31252531]
[68]
Zheng, Y.; Hu, X.; Liu, J.; Wu, G.; Zhou, H.; Zhu, M.; Zhai, Y.; Wu, L.; Shentu, J. Simple and sensitive analysis of blonanserin and blonanserin C in human plasma by liquid chromatography tandem mass spectrometry and its application. J. Anal. Methods Chem., 2014, 2014, 629343.
[http://dx.doi.org/10.1155/2014/629343] [PMID: 24678425]
[69]
Wen, Y-G.; Ni, X-J.; Zhang, M.; Liu, X.; Shang, D.W. Simultaneous determination of blonanserin and its metabolite in human plasma and urine by liquid chromatography-tandem mass spectrometry: Application to a pharmacokinetic study. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2012, 903, 46-52.
[http://dx.doi.org/10.1016/j.jchromb.2012.06.037] [PMID: 22818206]
[70]
Talluri, M.V.N.K.; Kandimalla, N.R.; Bandu, R.; Chundi, D.; Marupaka, R.; Srinivas, R. Selective separation, detection of zotepine and mass spectral characterization of degradants by LC-MS/MS/QTOF. J. Pharm. Anal., 2014, 4(2), 107-116.
[http://dx.doi.org/10.1016/j.jpha.2013.04.002] [PMID: 29403872]
[71]
Wang, S.T.; Li, Y. Development of a UPLC-MS/MS method for routine therapeutic drug monitoring of aripiprazole, amisulpride, olanzapine, paliperidone and ziprasidone with a discussion of their therapeutic reference ranges for Chinese patients. Biomed. Chromatogr., 2017, 31(8)
[http://dx.doi.org/10.1002/bmc.3928] [PMID: 28054367]
[72]
Zhou, Z.; Li, X.; Li, K.; Xie, Z.; Cheng, Z.; Peng, W.; Wang, F.; Zhu, R.; Li, H. Simultaneous determination of clozapine, olanzapine, risperidone and quetiapine in plasma by high-performance liquid chromatography-electrospray ionization mass spectrometry. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2004, 802(2), 257-262.
[http://dx.doi.org/10.1016/j.jchromb.2003.11.037] [PMID: 15018785]
[73]
Al-Dirbashi, O.Y.; Aboul-Enein, H.Y.; Al-Odaib, A.; Jacob, M.; Rashed, M.S. Rapid liquid chromatography-tandem mass spectrometry method for quantification of ziprasidone in human plasma. Biomed. Chromatogr., 2006, 20(4), 365-368.
[http://dx.doi.org/10.1002/bmc.571] [PMID: 16167302]
[74]
Mutlib, A.E.; Strupczewski, J.T. Picogram determination of iloperidone in human plasma by solid-phase extraction and by high-performance liquid chromatography-selected-ion monitoring electrospray mass spectrometry. J. Chromatogr. B Biomed. Appl., 1995, 669(2), 237-246.
[http://dx.doi.org/10.1016/0378-4347(95)00114-X] [PMID: 7581900]
[75]
Jia, M.; Li, J.; He, X.; Liu, M.; Zhou, Y.; Fan, Y.; Li, W. Simultaneous determination of iloperidone and its two active metabolites in human plasma by liquid chromatography-tandem mass spectrometry: Application to a pharmacokinetic study. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2013, 928, 52-57.
[http://dx.doi.org/10.1016/j.jchromb.2013.03.026] [PMID: 23618742]
[76]
Remmerie, B.M.M.; Sips, L.L.A.; de Vries, R.; de Jong, J.; Schothuis, A.M.; Hooijschuur, E.W.J.; van de Merbel, N.C. Validated method for the determination of risperidone and 9-hydroxyrisperidone in human plasma by liquid chromatography-tandem mass spectrometry. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2003, 783(2), 461-472.
[http://dx.doi.org/10.1016/S1570-0232(02)00715-8] [PMID: 12482489]
[77]
Bhatt, J.; Subbaiah, G.; Singh, S. Liquid chromatography/tandem mass spectrometry method for simultaneous determination of risperidone and its active metabolite 9-hydroxyrisperidone in human plasma. Rapid Commun. Mass Spectrom., 2006, 20(14), 2109-2114.
[http://dx.doi.org/10.1002/rcm.2537] [PMID: 16775814]
[78]
Flarakos, J.; Luo, W.; Aman, M.; Svinarov, D.; Gerber, N.; Vouros, P. Quantification of risperidone and 9-hydroxyrisperidone in plasma and saliva from adult and pediatric patients by liquid chromatography-mass spectrometry. J. Chromatogr. A, 2004, 1026(1-2), 175-183.
[http://dx.doi.org/10.1016/j.chroma.2003.10.138] [PMID: 14763744]
[79]
Vanwong, N.; Prommas, S.; Puangpetch, A.; Hongkaew, Y.; Nuntamool, N.; Nakorn, C.N.; Ngamsamut, N.; Limsila, P.; Sukasem, C. Development and validation of liquid chromatography/tandem mass spectrometry analysis for therapeutic drug monitoring of risperidone and 9-hydroxyrisperidone in pediatric patients with autism spectrum disorders. J. Clin. Lab. Anal., 2016, 30(6), 1236-1246.
[http://dx.doi.org/10.1002/jcla.22009] [PMID: 27346210]
[80]
De Meulder, M.; Remmerie, B.M.M.; de Vries, R.; Sips, L.L.A.; Boom, S.; Hooijschuur, E.W.J.; van de Merbel, N.C.; Timmerman, P.M.M.B.L.; Validated, L.C. Validated LC-MS/MS methods for the determination of risperidone and the enantiomers of 9-hydroxyrisperidone in human plasma and urine. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2008, 870(1), 8-16.
[http://dx.doi.org/10.1016/j.jchromb.2008.04.041] [PMID: 18571483]
[81]
Aravagiri, M.; Marder, S.R. Simultaneous determination of risperidone and 9-hydroxyrisperidone in plasma by liquid chromatography/electrospray tandem mass spectrometry. J. Mass Spectrom., 2000, 35(6), 718-724.
[http://dx.doi.org/10.1002/1096-9888(200006)35:6<718:AID-JMS999>3.0.CO;2-O] [PMID: 10862124]
[82]
Aravagiri, M.; Marder, S.R.; Van Putten, T.; Midha, K.K. Determination of risperidone in plasma by high-performance liquid chromatography with electrochemical detection: Application to therapeutic drug monitoring in schizophrenic patients. J. Pharm. Sci., 1993, 82(5), 447-449.
[http://dx.doi.org/10.1002/jps.2600820503] [PMID: 7689651]
[83]
Davis, P.C.; Bravo, O.; Gehrke, M.; Azumaya, C.T. Development and validation of an LC-MS/MS method for the determination of quetiapine and four related metabolites in human plasma. J. Pharm. Biomed. Anal., 2010, 51(5), 1113-1119.
[http://dx.doi.org/10.1016/j.jpba.2009.11.018] [PMID: 20022726]
[84]
Carreño, F.; Helfer, V.E.; Staudt, K.J.; Olivo, L.B.; Barreto, F.; Herrmann, A.P.; Rates, S.M.K.; Dalla Costa, T. Quantification of neurotransmitters in microdialysate samples following quetiapine dosing to schizophrenia phenotyped rats using a validated LC-MS/MS method. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2020, 1155, 122282.
[http://dx.doi.org/10.1016/j.jchromb.2020.122282] [PMID: 32771966]
[85]
Barrett, B. Holčapek, M.; Huclová, J.; Borek-Dohalský, V.; Fejt, P.; Němec, B.; Jelínek, I. Validated HPLC-MS/MS method for determination of quetiapine in human plasma. J. Pharm. Biomed. Anal., 2007, 44(2), 498-505.
[http://dx.doi.org/10.1016/j.jpba.2007.03.034] [PMID: 17499470]
[86]
Li, M.; Zhang, S.; Shi, A.; Qi, W.; Liu, Y. Determination of quetiapine in human plasma by LC-MS/MS and its application in a bioequivalence study. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2017, 1060, 10-14.
[http://dx.doi.org/10.1016/j.jchromb.2017.05.031] [PMID: 28578191]
[87]
Pan, R.N.; Kuo, B.P.C.; Pao, L.H. Validated LC-MS-MS method for the determination of quetiapine in human plasma: Application to a pharmacokinetic study. J. Chromatogr. Sci., 2012, 50(3), 277-282.
[http://dx.doi.org/10.1093/chromsci/bms001] [PMID: 22337805]
[88]
Nirogi, R.; Bhyrapuneni, G.; Kandikere, V.; Mudigonda, K.; Ajjala, D.; Mukkanti, K. Sensitive liquid chromatography tandem mass spectrometry method for the quantification of Quetiapine in plasma. Biomed. Chromatogr., 2008, 22(10), 1043-1055.
[http://dx.doi.org/10.1002/bmc.1012] [PMID: 18781706]
[89]
Xiong, X.; Yang, L.; Duan, J. Development and validation of a sensitive and robust LC-MS/MS with electrospray ionization method for simultaneous quantitation of quetiapine and its active metabolite norquetiapine in human plasma. Clin. Chim. Acta, 2013, 423, 69-74.
[http://dx.doi.org/10.1016/j.cca.2013.04.016] [PMID: 23623924]
[90]
Kundlik, M.L.; Kambli, S.; Shah, V.; Patel, Y.; Gupta, S.; Sharma, R.; Zaware, B.; Kuchekar, S.R. Quantification of quetiapine in human plasma by LC-MS-MS. Chromatographia, 2009, 70, 1587-1592.
[http://dx.doi.org/10.1365/s10337-009-1353-z]
[91]
Binz, T.M.; Yegles, M.; Schneider, S.; Neels, H.; Crunelle, C.L. Time resolved analysis of quetiapine and 7-OH-quetiapine in hair using LC/MS-MS. Forensic Sci. Int., 2014, 242, 200-203.
[http://dx.doi.org/10.1016/j.forsciint.2014.07.002] [PMID: 25072665]
[92]
Yang, X.; Poddar, I.; Hernandez, C.M.; Terry, A.V., Jr; Bartlett, M.G. Simultaneous quantitation of quetiapine and its active metabolite norquetiapine in rat plasma and brain tissue by high performance liquid chromatography/electrospray ionization tandem mass spectrometry (LC-MS/MS). J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2015, 1002, 71-77.
[http://dx.doi.org/10.1016/j.jchromb.2015.08.011] [PMID: 26313131]
[93]
Bhavyasri, K.; Balaram, V.; Nageswarao, R.; Rambabu, D.; Ajitha, M.; Challa, B. A validated bioanalytical method for quantification of ziprasidone in rabbit plasma by LC-MS/MS: Application to a pharmacokinetic study. Br. J. Pharm. Res., 2015, 6, 322-332.
[http://dx.doi.org/10.9734/BJPR/2015/12137]
[94]
Miao, Z.; Kamel, A.; Prakash, C. Characterization of a novel metabolite intermediate of ziprasidone in hepatic cytosolic fractions of rat, dog, and human by ESI-MS/MS, hydrogen/deuterium exchange, and chemical derivatization. Drug Metab. Dispos., 2005, 33(7), 879-883.
[http://dx.doi.org/10.1124/dmd.105.004036] [PMID: 15821046]
[95]
Menacherry, S.D.; Stamm, G.E.; Chu, S.Y. A sensitive and specific method for assay of sertindole and its metabolites in human, rat, dog, and mouse plasma using HPLC with tandem mass spectrometric detection. J. Liq. Chromatogr. Relat. Technol., 1997, 20, 2241-2257.
[http://dx.doi.org/10.1080/10826079708006560]
[96]
Niederländer, H.A.G.; Koster, E.H.M.; Hilhorst, M.J.; Metting, H.J.; Eilders, M.; Ooms, B.; de Jong, G.J. High throughput therapeutic drug monitoring of clozapine and metabolites in serum by on-line coupling of solid phase extraction with liquid chromatography-mass spectrometry. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2006, 834(1-2), 98-107.
[http://dx.doi.org/10.1016/j.jchromb.2006.02.042] [PMID: 16527550]
[97]
Wohlfarth, A.; Toepfner, N.; Hermanns-Clausen, M.; Auwärter, V. Sensitive quantification of clozapine and its main metabolites norclozapine and clozapine-N-oxide in serum and urine using LC-MS/MS after simple liquid-liquid extraction work-up. Anal. Bioanal. Chem., 2011, 400(3), 737-746.
[http://dx.doi.org/10.1007/s00216-011-4831-8] [PMID: 21394453]
[98]
Nageswara Rao, R.; Guru Prasad, K.; Khalid, S.; Praneetha, K.S.; Dodda, Di.; Veeresham, C. Liquid chromatography-mass spectrometry determination of iloperidone on rat dried blood spots: Application to pharmacokinetics. Anal. Methods, 2017, 9, 5749-5756.
[http://dx.doi.org/10.1039/C7AY01589E]
[99]
Albayrak, M.; Kadioglu, Y.; Yaman, M.E.; Senol, O.; Oral, E. Determination of olanzapine for therapeutic drug monitoring in schizophrenia patients by LC/MS Method. Biomed. Chromatogr., 2018, e4468.
[http://dx.doi.org/10.1002/bmc.4468] [PMID: 30549068]
[100]
OʼHalloran, S.J.; Wong, A.; Joyce, D.A. A liquid chromatography-tandem mass spectrometry method for quantifying amisulpride in human plasma and breast milk, applied to measuring drug transfer to a fully breast-fed neonate. Ther. Drug Monit., 2016, 38(4), 493-498.
[http://dx.doi.org/10.1097/FTD.0000000000000300] [PMID: 27027463]
[101]
Ruan, C.J.; Guo, W.; Zhou, M.; Guo, G.X.; Wang, C.Y.; Li, W.B.; de Leon, J. Quantitative determination of risperidone, paliperidone and olanzapine in human serum by liquid chromatography-tandem mass spectrometry coupled with on-line solid-phase extraction. Biomed. Chromatogr., 2018, 32(7), e4209.
[http://dx.doi.org/10.1002/bmc.4209] [PMID: 29473184]
[102]
Sampedro, M.C.; Unceta, N.; Gómez-Caballero, A.; Callado, L.F.; Morentin, B.; Goicolea, M.A.; Meana, J.J.; Barrio, R.J. Screening and quantification of antipsychotic drugs in human brain tissue by liquid chromatography-tandem mass spectrometry: Application to postmortem diagnostics of forensic interest. Forensic Sci. Int., 2012, 219(1-3), 172-178.
[http://dx.doi.org/10.1016/j.forsciint.2012.01.002] [PMID: 22265463]
[103]
Wong, A.S.Y.; Choi, T.L.S.; Kwok, K.Y.; Wong, J.K.Y.; Wan, T.S.M.; Ho, E.N.M. Doping control analysis of antipsychotics and other prohibited substances in equine plasma by liquid chromatography/tandem mass spectrometry. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2020, 1147, 122132.
[http://dx.doi.org/10.1016/j.jchromb.2020.122132] [PMID: 32417678]
[104]
Johansen, S.S. Detection of the antipsychotic drug quetiapine in the blood, urine and hair samples of the victim of a drug-facilitated sexual assault. Forensic Sci. Int., 2017, 270, e12-e15.
[http://dx.doi.org/10.1016/j.forsciint.2016.12.010] [PMID: 28012825]
[105]
Tu, J.Y.; Xu, P.; Xu, D.H.; De Li, H. UPLC-MS-MS analysis of quetiapine and its two active metabolites, 7-hydroxyquetiapine and 7-hydroxy-N-dealkylquetiapine, in rat plasma and cerebrospinal fluid. Chromatographia, 2008, 68, 525-532.
[http://dx.doi.org/10.1365/s10337-008-0770-8]
[106]
Čarapić, M.; Nikolic, K.; Marković, B.; Petković, M.; Pavlovic, M.; Agbaba, D. Ultra-performance liquid chromatography tandem mass spectrometry for the rapid, simultaneous analysis of ziprasidone and its impurities. Biomed. Chromatogr., 2019, 32(2), e4384.
[http://dx.doi.org/10.1002/bmc.4384] [PMID: 30215855]
[107]
Li, K-Y.; Zhou, Y-G.; Ren, H-Y.; Wang, F.; Zhang, B-K.; Li, H-D. Ultra-performance liquid chromatography-tandem mass spectrometry for the determination of atypical antipsychotics and some metabolites in in vitro samples. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2007, 850(1-2), 581-585.
[http://dx.doi.org/10.1016/j.jchromb.2006.12.051] [PMID: 17257911]
[108]
Raggi, M.A.; Bugamelli, F.; Sabbioni, C.; Saracino, M.A.; Petio, C. HPLC-DAD determination of plasma levels of the antipsychotic risperidone and its main metabolite for toxicological purposes. J. Sep. Sci., 2005, 28(3), 245-250.
[http://dx.doi.org/10.1002/jssc.200401939] [PMID: 15776926]
[109]
de Diego, M.; Campos, C.; Correa, D.; Mennickent, S.; Godoy, R.; Vergara, C. Degradation studies of quetiapine fumarate by liquid chromatography-diode array detection and tandem mass spectrometry methods. Biomed. Chromatogr., 2019, 33(11), e4655.
[http://dx.doi.org/10.1002/bmc.4655] [PMID: 31322744]
[110]
Radha Krishna, S.; Rao, B.M.; Someswara Rao, N. A validated stability indicating HPLC method for the determination of related substances in quetiapine fumarate. Rasayan J. Chem., 2008, 1, 466-474.
[111]
Soma Raju, I.V.; Raghuram, P.; Sriramulu, J. Development and validation of a new analytical method for the determination of related components in quetiapine hemifumarate. Chromatographia, 2009, 70, 545-550.
[http://dx.doi.org/10.1365/s10337-009-1183-z]
[112]
Karaca, S.A. Uğur, D.Y. Determination of iloperidone in pharmaceuticals by validated high-performance liquid chromatography. Anal. Lett., 2018, 51, 24-32.
[http://dx.doi.org/10.1080/00032719.2017.1302462]
[113]
Woestenborghs, R.; Lorreyne, W.; Van Rompaey, F.; Heykants, J. Determination of risperidone and 9-hydroxyrisperidone in plasma, urine and animal tissues by high-performance liquid chromatography. J. Chromatogr. B Biomed. Sci. Appl., 1992, 583(2), 223-230.
[http://dx.doi.org/10.1016/0378-4347(92)80556-6] [PMID: 1282517]
[114]
Pavlovic, M.; Malesevic, M.; Nikolic, K.; Agbaba, D. Development and validation of an HPLC method for determination of ziprasidone and its impurities in pharmaceutical dosage forms. J. AOAC Int., 2011, 94(3), 713-722.
[http://dx.doi.org/10.1093/jaoac/94.3.713] [PMID: 21796998]
[115]
Rosa, P.C.P.; Pires, I.F.R.; Markman, B.E.O.; Perazzo, F.F. Development and validation of RP-HPLC method for the determination of related compounds in quetiapine hemifumarate raw material and tablets. J. Appl. Pharm. Sci., 2013, 3, 6-15.
[http://dx.doi.org/10.7324/JAPS.2013.3802]
[116]
Davydovych, S.; Halkevych, I.; Korobova, O.; Humenyuk, S. Solid-phase extraction for RP-HPLC/UV determination of ziprasidone at presence its main metabolite in urine. J. Appl. Pharm. Sci., 2017, 7, 1-6.
[http://dx.doi.org/10.7324/JAPS.2017.70501]
[117]
Singh, A.; Rao, B.M.; Deshpande, G.R.; Sangaraju, S.; Srinivasu, M.K.; Lalitha Devi, M.; Satyanarayana, P.V.V.; Chandrasekhar, K.B. A rapid stability-indicating LC method for ziprasidone hydrochloride. Chromatographia, 2007, 65, 191-196.
[http://dx.doi.org/10.1365/s10337-006-0125-2]
[118]
Bansal, R.; Chandrabose, K.; Hari Narayana Moorthy, N.S.; Singh, D.P.; Singh, D.; Trivedi, P. A new simple and rapid validated RP-HPLC method for determination of ziprasidone in ziprasidone capsules. J. Saudi Chem. Soc., 2016, 20, S161-S167.
[http://dx.doi.org/10.1016/j.jscs.2012.10.005]
[119]
Frahnert, C.; Rao, M.L.; Grasmäder, K. Analysis of eighteen antidepressants, four atypical antipsychotics and active metabolites in serum by liquid chromatography: A simple tool for therapeutic drug monitoring. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2003, 794(1), 35-47.
[http://dx.doi.org/10.1016/S1570-0232(03)00393-3] [PMID: 12888196]
[120]
Belal, F.; Elbrashy, A.; Eid, M.; Nasr, J.J. Stability-indicating HPLC method for the determination of quetiapine: Application to tablets and human plasma. J. Liq. Chromatogr. Relat. Technol., 2008, 31, 1283-1298.
[http://dx.doi.org/10.1080/10826070802019681]
[121]
Marghade, S.; Musmade, P.B.; Moorkoth, S. High-performance liquid chromatographic assay for ziprasidone in plasma samples: Application to pharmacokinetic studies in rats. J. Chromatogr. Sci., 2012, 50(10), 902-908.
[http://dx.doi.org/10.1093/chromsci/bms088] [PMID: 22677485]
[122]
Mercolini, L.; Grillo, M.; Bartoletti, C.; Boncompagni, G.; Raggi, M.A. Simultaneous analysis of classical neuroleptics, atypical antipsychotics and their metabolites in human plasma. Anal. Bioanal. Chem., 2007, 388(1), 235-243.
[http://dx.doi.org/10.1007/s00216-007-1195-1] [PMID: 17340084]
[123]
Mandpe, L.; Kyadarkunte, A.; Pokharkar, V. High-performance liquid chromatographic method for simultaneous determination of iloperidone and idebenone in spiked plasma. Int. J. Chem. Anal. Sci., 2013, 4, 19-23.
[http://dx.doi.org/10.1016/j.ijcas.2013.02.001]
[124]
Chhalotiya, U.K.; Bhatt, K.K.; Shah, D.A.; Patel, J.R. Liquid chromatographic method for the quantification of antipsychotic agent iloperidone in pharmaceutical formulation, ISRN. Anal. Chem., 2012, 2012, 1-6.
[http://dx.doi.org/10.5402/2012/963276]
[125]
Filipce, A.; Naumovska, Z.; Nestorovska, A.K.; Sterjev, Z.; Brezovska, K.; Tonic-Ribarska, J.; Grozdanova, A.; Suturkova, L.; Raleva, M. Evaluation of correlation between the pharmacogenetic profiles of risperidone treated psychiatry patients with plasma and urine concentration of risperidone and its active moiety 9-OH risperidone determined with optimized bioanalytical LC method. Prilozi (Makedon. Akad. Nauk. Umet. Odd. Med. Nauki), 2018, 39(2-3), 97-106.
[http://dx.doi.org/10.2478/prilozi-2018-0047] [PMID: 30864366]
[126]
Titier, K.; Bouchet, S.; Péhourcq, F.; Moore, N.; Molimard, M. High-performance liquid chromatographic method with diode array detection to identify and quantify atypical antipsychotics and haloperidol in plasma after overdose. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2003, 788(1), 179-185.
[http://dx.doi.org/10.1016/S1570-0232(02)01003-6] [PMID: 12668083]
[127]
Yasui-Furukori, N.; Inoue, Y.; Tateishi, T. Determination of a new atypical antipsychotic agent perospirone and its metabolite in human plasma by automated column-switching high-performance liquid chromatography. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2003, 789(2), 239-245.
[http://dx.doi.org/10.1016/S1570-0232(03)00067-9] [PMID: 12742115]
[128]
Mercolini, L.; Protti, M.; Fulgenzi, G.; Mandrioli, R.; Ghedini, N.; Conca, A.; Raggi, M.A. A fast and feasible microextraction by packed sorbent (MEPS) procedure for HPLC analysis of the atypical antipsychotic ziprasidone in human plasma. J. Pharm. Biomed. Anal., 2014, 88, 467-471.
[http://dx.doi.org/10.1016/j.jpba.2013.09.019] [PMID: 24176751]
[129]
Sachse, J.; Köller, J.; Härtter, S.; Hiemke, C. Automated analysis of quetiapine and other antipsychotic drugs in human blood by high performance-liquid chromatography with column-switching and spectrophotometric detection. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2006, 830(2), 342-348.
[http://dx.doi.org/10.1016/j.jchromb.2005.11.032] [PMID: 16337441]
[130]
Raggi, M.A.; Casamenti, G.; Mandrioli, R.; Izzo, G.; Kenndler, E. Quantitation of olanzapine in tablets by HPLC, CZE, derivative spectrometry and linear voltammetry. J. Pharm. Biomed. Anal., 2000, 23(6), 973-981.
[http://dx.doi.org/10.1016/S0731-7085(00)00382-4] [PMID: 11095298]
[131]
Nagasaki, T.; Ohkubo, T.; Sugawara, K.; Yasui, N.; Furukori, H.; Kaneko, S. Determination of risperidone and 9-hydroxyrisperidone in human plasma by high-performance liquid chromatography: Application to therapeutic drug monitoring in Japanese patients with schizophrenia. J. Pharm. Biomed. Anal., 1999, 19(3-4), 595-601.
[http://dx.doi.org/10.1016/S0731-7085(98)00261-1] [PMID: 10704125]
[132]
Lerena, A.; Berecz, R.; Dorado, P.; De la Garza, C.S.; Norberto, M.J.; Cáceres, M.; Gutiérrez, J.R. Determination of risperidone and 9-hydroxyrisperidone in human plasma by liquid chromatography: Application to the evaluation of CYP2D6 drug interactions, J. Chromatogr. B Anal. Technol. Biomed. Life Sci., 2003, 783, 213-219.
[http://dx.doi.org/10.1016/S1570-0232(02)00661-X]
[133]
Weigmann, H.; Härtter, S.; Maehrlein, S.; Kiefer, W.; Krämer, G.; Dannhardt, G.; Hiemke, C. Simultaneous determination of olanzapine, clozapine and demethylated metabolites in serum by on-line column-switching high-performance liquid chromatography. J. Chromatogr. B Biomed. Sci. Appl., 2001, 759(1), 63-71.
[http://dx.doi.org/10.1016/S0378-4347(01)00215-8] [PMID: 11499630]
[134]
Sachse, J.; Härtter, S.; Hiemke, C. Automated determination of ziprasidone by HPLC with column switching and spectrophotometric detection. Ther. Drug Monit., 2005, 27(2), 158-162.
[http://dx.doi.org/10.1097/01.ftd.0000150879.36296.4d] [PMID: 15795645]
[135]
Kovatsi, L.; Redifis, K.; Mihailidou, K.; Pavlidis, P.; Samanidou, V. A validated UHPLC-diode array detector method for the bioanalysis of atypical antipsychotics in whole blood, urine and cerebrospinal fluid following SPE. Bioanalysis, 2012, 4(24), 2929-2938.
[http://dx.doi.org/10.4155/bio.12.276] [PMID: 23244283]
[136]
Siva Selva Kumar, M.; Ramanathan, M. Concurrent determination of olanzapine, risperidone and 9-hydroxyrisperidone in human plasma by ultra performance liquid chromatography with diode array detection method: Application to pharmacokinetic study. Biomed. Chromatogr., 2016, 30(2), 263-268.
[http://dx.doi.org/10.1002/bmc.3545] [PMID: 26129833]
[137]
Bindu, K.H.; Reddy, I.U.; Anjaneyulu, Y.; Suryanarayana, M.V. A stability-indicating ultra-performance liquid chromatographic method for estimation of related substances and degradants in paliperidone active pharmaceutical ingredient and its pharmaceutical dosage forms. J. Chromatogr. Sci., 2012, 50(4), 368-372.
[http://dx.doi.org/10.1093/chromsci/bms011] [PMID: 22407348]
[138]
Pandeti, S.; Rout, T.K.; Tadigoppula, N.; Thota, J.R. Identification of stress degradation products of iloperidone using liquid chromatography coupled with an Orbitrap mass spectrometer. Rapid Commun. Mass Spectrom., 2017, 31(16), 1324-1332.
[http://dx.doi.org/10.1002/rcm.7907] [PMID: 28556266]
[139]
Peng, M.; Liu, J.; Lu, D.; Yang, Y.J. Development and validation of a stability-indicating gas chromatographic method for quality control of residual solvents in blonanserin: A novel atypical antipsychotic agent. J. Chromatogr. Sci., 2012, 50(8), 727-732.
[http://dx.doi.org/10.1093/chromsci/bms069] [PMID: 22595261]
[140]
Miller, C.; Pleitez, O.; Anderson, D.; Mertens-Maxham, D.; Wade, N. Asenapine (Saphris®): GC-MS method validation and the postmortem distribution of a new atypical antipsychotic medication. J. Anal. Toxicol., 2013, 37(8), 559-564.
[http://dx.doi.org/10.1093/jat/bkt076] [PMID: 24009049]
[141]
Logarinho, F.; Rosado, T.; Lourenço, C.; Barroso, M.; Araujo, A.R.T.S.; Gallardo, E. Determination of antipsychotic drugs in hospital and wastewater treatment plant samples by gas chromatography/tandem mass spectrometry. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2016, 1038, 127-135.
[http://dx.doi.org/10.1016/j.jchromb.2016.10.031] [PMID: 28029546]
[142]
Lu, M.L.; Lin, C.H.; Chen, Y.C.; Yang, H.C.; Wu, T.H. Determination of olanzapine and N-desmethyl-olanzapine in plasma using a reversed-phase HPLC coupled with coulochemical detection: Correlation of olanzapine or N-desmethyl-olanzapine concentration with metabolic parameters. PLoS One, 2013, 8(5), e65719.
[http://dx.doi.org/10.1371/journal.pone.0065719] [PMID: 23741510]
[143]
Riman, D.; Rozsypal, J.; Halouzka, V.; Hrbac, J.; Jirovsky, D. The use of micro carbon pencil lead electrode for sensitive HPLC-ED analysis of selected antipsychotic drugs. Microchem. J., 2020, 154, 104606.
[http://dx.doi.org/10.1016/j.microc.2020.104606]
[144]
Saracino, M.A.; Gandolfi, O.; Dall’olio, R.; Albers, L.; Kenndler, E.; Raggi, M.A. Determination of Olanzapine in rat brain using liquid chromatography with coulometric detection and a rapid solid-phase extraction procedure. J. Chromatogr. A, 2006, 1122(1-2), 21-27.
[http://dx.doi.org/10.1016/j.chroma.2006.04.011] [PMID: 16678187]
[145]
Tumpa, A. Stajić A.; Jančić-Stojanović B.; Medenica, M. Quality by Design in the development of hydrophilic interaction liquid chromatography method with gradient elution for the analysis of olanzapine. J. Pharm. Biomed. Anal., 2017, 134, 18-26.
[http://dx.doi.org/10.1016/j.jpba.2016.11.010] [PMID: 27871053]
[146]
De Meulder, M.; Waldron, M.P.; Li, L.; Peay, M.G.; Tingler, M.J.; Hidy, B.J.; Verhaeghe, T.; Jenkins, R.G. Development and validation of HILIC-ESI/MS/MS methods for simultaneous quantitation of several antipsychotics in human plasma and blood. Bioanalysis, 2016, 8(8), 765-794.
[http://dx.doi.org/10.4155/bio.16.27] [PMID: 27005848]
[147]
Saracino, M.A.; Lazzara, G.; Prugnoli, B.; Raggi, M.A. Rapid assays of clozapine and its metabolites in dried blood spots by liquid chromatography and microextraction by packed sorbent procedure. J. Chromatogr. A, 2011, 1218(16), 2153-2159.
[http://dx.doi.org/10.1016/j.chroma.2011.01.071] [PMID: 21397237]
[148]
Tanaka, O.; Kondo, T.; Kaneko, S.; Mihara, K.; Otani, K.; Tokinaga, N. A method for rapid determination of zotepine by gas chromatography-mass spectrometry. Ther. Drug Monit., 1996, 18(3), 294-296.
[http://dx.doi.org/10.1097/00007691-199606000-00013] [PMID: 8738771]
[149]
Hattori, H.; Iwai, M.; Ogawa, T. Simple analysis of blonanserin, a novel antipsychotic agent, in human plasma by GC-MS. Forensic Toxicol., 2010, 28, 105-109.
[http://dx.doi.org/10.1007/s11419-010-0090-1]
[150]
Bondesson, U.; Lindström, L.H. Determination of clozapine and its N-demethylated metabolite in plasma by use of gas chromatography-mass spectrometry with single ion detection. Psychopharmacology (Berl.), 1988, 95(4), 472-475.
[http://dx.doi.org/10.1007/BF00172957] [PMID: 3145517]
[151]
López-Guarnido, O.; Tabernero, M.J.; Hernández, A.F.; Rodrigo, L.; Bermejo, A.M. Rapid determination of quetiapine in blood by gas chromatography-mass spectrometry. Application to post-mortem cases. J. Appl. Toxicol., 2014, 34(10), 1104-1108.
[http://dx.doi.org/10.1002/jat.2944] [PMID: 24127231]
[152]
Hillaert, S.; Snoeck, L.; Van Den Bossche, W. Optimization and validation of a capillary zone electrophoretic method for the simultaneous analysis of four atypical antipsychotics., 2004, 1033, 357-362.
[http://dx.doi.org/10.1016/j.chroma.2004.01.057]
[153]
Schatz, D.S.; Saria, A. Simultaneous determination of paroxetine, risperidone and 9-hydroxyrisperidone in human plasma by high-performance liquid chromatography with coulometric detection. Pharmacology, 2000, 60(1), 51-56.
[http://dx.doi.org/10.1159/000028347] [PMID: 10629444]
[154]
Bin Tzeng, T.; Stamm, G.S. yie Chu, Sensitive method for the assay of sertindole in plasma by high-performance liquid chromatography and fluorimetric detection. J. Chromatogr. B Biomed. Sci. Appl., 1994, 661, 299-306.
[http://dx.doi.org/10.1016/0378-4347(94)00356-4]
[155]
Bellomarino, S.A.; Brown, A.J.; Conlan, X.A.; Barnett, N.W. Preliminary evaluation of monolithic column high-performance liquid chromatography with tris(2,2′-bipyridyl)ruthenium(II) chemiluminescence detection for the determination of quetiapine in human body fluids. Talanta, 2009, 77(5), 1873-1876.
[http://dx.doi.org/10.1016/j.talanta.2008.10.023] [PMID: 19159813]

Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy