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Current Psychiatry Research and Reviews

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ISSN (Print): 2666-0822
ISSN (Online): 2666-0830

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Research Article

Is Breastfeeding Duration Associated with Risk of Developing ASD?

Author(s): Ensiyeh Jenabi, Mahdieh Seyedi, Saeid Bashirian and Salman Khazaei*

Volume 19, Issue 1, 2023

Published on: 30 September, 2022

Page: [89 - 94] Pages: 6

DOI: 10.2174/2666082218666220822121039

Price: $65

Abstract

Background: There are few studies in the world on the duration of breastfeeding and the risk of autism. To our knowledge, no study has yet explained the association between breastfeeding duration and ASD in Iran.

Aims: The present study evaluated the association between breastfeeding and the risk of ASD in offspring in the west of Iran.

Methods: This case-control study was performed on 100 children aged 3-14 years who had a medical record in the Autism Spectrum Disorder Research Center and the Autism Association of Hamadan and were diagnosed with autism according to the Diagnostic and Statistical Manual of mental disorders (DSM-5) criteria. The control group included healthy children who had active family record in comprehensive health service centers. All the analyses were performed using Stata software version 14. The significance level was considered less than 0.05.

Results: After adjusting for other variables, each increase in the month of breastfeeding was associated with a 5% decrease in odds of ASD (OR=0.95 (95% CI: 0.91, 0.99), p=0.03). The odds of ASD in boys were significantly higher (OR=3.85 (95% CI: 1.91, 7.76), p<0.001). Moreover, drug use (OR=0.01), history of autism (OR=6.62), and history of psychiatry disorder (OR=7.2) were significantly associated with increased odds of ASD (p<0.05).

Conclusion: These findings showed that breastfeeding duration can be a protective factor for ASD. Therefore, policymakers and health staff can reduce the risk of autism by promoting increased breastfeeding duration, especially for children with a high risk for autism.

Keywords: Autism Spectrum disorders, Breastfeeding, case-control

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[1]
Saab D, Chaaya M, Boustany RM. National prevalence and correlates of autism: A lebanese crosssectional study Autism Open Access 2018; 8(1): 2.
[http://dx.doi.org/10.4172/2165-7890.1000223]
[2]
Baxter AJ, Brugha TS, Erskine HE, Scheurer RW, Vos T, Scott JG. The epidemiology and global burden of autism spectrum disorders. Psychol Med 2015; 45(3): 601-13.
[http://dx.doi.org/10.1017/S003329171400172X] [PMID: 25108395]
[3]
Lord C, Elsabbagh M, Baird G, Veenstra-Vanderweele J. Autism spectrum disorder. Lancet 2018; 392(10146): 508-20.
[http://dx.doi.org/10.1016/S0140-6736(18)31129-2] [PMID: 30078460]
[4]
Fujiwara T, Morisaki N, Honda Y, Sampei M, Tani Y. Chemicals, nutrition, and autism spectrum disorder: A mini-review. Front Neurosci 2016; 10: 174.
[http://dx.doi.org/10.3389/fnins.2016.00174] [PMID: 27147957]
[5]
Cogley C, O’Reilly H, Bramham J, Downes M. A systematic review of the risk factors for autism spectrum disorder in children born preterm. Child Psychiatry Hum Dev 2021; 52(5): 841-55.
[PMID: 32980936]
[6]
Boucher O, Julvez J, Guxens M, et al. Association between breastfeeding duration and cognitive development, autistic traits and ADHD symptoms: A multicenter study in Spain. Pediatr Res 2017; 81(3): 434-42.
[http://dx.doi.org/10.1038/pr.2016.238] [PMID: 27846197]
[7]
Belfort MB, Rifas-Shiman SL, Kleinman KP, et al. Infant feeding and childhood cognition at ages 3 and 7 years: Effects of breastfeeding duration and exclusivity. JAMA Pediatr 2013; 167(9): 836-44.
[http://dx.doi.org/10.1001/jamapediatrics.2013.455] [PMID: 23896931]
[8]
Quigley MA, Hockley C, Carson C, Kelly Y, Renfrew MJ, Sacker A. Breastfeeding is associated with improved child cognitive development: A population-based cohort study. J Pediatr 2012; 160(1): 25-32.
[http://dx.doi.org/10.1016/j.jpeds.2011.06.035] [PMID: 21839469]
[9]
Husk JS, Keim SA. Breastfeeding and autism spectrum disorder in the National Survey of Children’s Health. Epidemiology 2015; 26(4): 451-7.
[http://dx.doi.org/10.1097/EDE.0000000000000290] [PMID: 25872161]
[10]
Field SS. Interaction of genes and nutritional factors in the etiology of autism and attention deficit/hyperactivity disorders: A case control study. Med Hypotheses 2014; 82(6): 654-61.
[http://dx.doi.org/10.1016/j.mehy.2014.02.021] [PMID: 24685108]
[11]
American Psychiatric Association D Diagnostic and statistical manual of mental disorders: DSM-5. Washington, DC: American Psychiatric Association 2013.
[12]
Shamsedine L, Mailhac A, Badaoui A, et al. Breastfeeding association with autism spectrum disorders: A case-control study from Lebanon. Res Autism Spectr Disord 2020; 78: 101651.
[http://dx.doi.org/10.1016/j.rasd.2020.101651]
[13]
Brown CM, Austin DW. Autistic disorder and phospholipids: A review. Prostaglandins Leukot Essent Fatty Acids 2011; 84(1-2): 25-30.
[http://dx.doi.org/10.1016/j.plefa.2010.09.007] [PMID: 20970971]
[14]
Lucas RF, Cutler A. Dysregulated breastfeeding behaviors in children later diagnosed with autism. J Perinat Educ 2015; 24(3): 171-80.
[http://dx.doi.org/10.1891/1058-1243.24.3.171] [PMID: 26834438]
[15]
Shafai T, Mustafa M, Hild T, Mulari J, Curtis A. The association of early weaning and formula feeding with autism spectrum disorders. Breastfeed Med 2014; 9(5): 275-6.
[http://dx.doi.org/10.1089/bfm.2013.0104] [PMID: 24506526]
[16]
Tseng PT, Chen YW, Stubbs B, et al. Maternal breastfeeding and autism spectrum disorder in children: A systematic review and meta-analysis. Nutr Neurosci 2019; 22(5): 354-62.
[http://dx.doi.org/10.1080/1028415X.2017.1388598] [PMID: 29046132]
[17]
Guisso DR, Saadeh FS, Saab D, et al. Association of autism with maternal infections, perinatal and other risk factors: A case-control study. J Autism Dev Disord 2018; 48(6): 2010-21.
[http://dx.doi.org/10.1007/s10803-017-3449-x] [PMID: 29332178]
[18]
Saunders A, Woodland J, Gander S. A comparison of prenatal exposures in children with and without a diagnosis of autism spectrum disorder. Cureus 2019; 11(7): e5223.
[http://dx.doi.org/10.7759/cureus.5223] [PMID: 31565625]
[19]
Xie S, Karlsson H, Dalman C, Widman L, Rai D, Gardner RM, et al. Family history of mental and neurological disorders and risk of autism. JAMA Netw Open 2019; 2(3): e190154.
[http://dx.doi.org/10.1001/jamanetworkopen.2019.0154]
[20]
Guisso DR, Saadeh FS, Saab D. El Deek J, Chamseddine S, El Hassan HA, Majari G, Boustany RM. Association of autism with maternal infections, perinatal and other risk factors: a case-control study. J Aut Develop Disor 2018; 48(6): 2010-21.

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