[1]
Lountos, R.; Zhao, X. Z.; Kiselev, E.; Tropea, J.; Needle, D.; Pommier, Y.; Burke, T. R., Jr.; Waugh, D. Identification of ligand binding hot spot and structural motifs replicating aspects of Tdp1 phosphoryl recognition by crystrallographic fragment coctail screening. Nucleic Acids Res., 2019, 47, 10134-10150.
[2]
Qi, J.; Hymel, D.; Nelson, C. G.; Burke, T. R., Jr.; Rader, C. Conventional and chemically programmed asymmetric bispecific antibodies targeting folate receptor 1. Frontiers Immun., 2019, 10, 1994.
[http://dx.doi.org/10.3389/fimmu.2019.01994]
[http://dx.doi.org/10.3389/fimmu.2019.01994]
[3]
Passos, D.; Li, M.; Jóźwik, l. K.; Zhao, X. Z.; Santos, D. M.; Yang, R.; Jeon, Y.; Forli, S.; Hughes, S. H.; Burke, T. R., Jr.; Craigie, R.; Lyumkis, D. Structural basis for strand transfer inhibitor binding to HIV intasomes. Science, 2020, 367, 810-814.
[4]
Qi, J.; Tsuji, K.; Hymel, D.; Burke, T. R., Jr.; Hudecek, M.; Rader, C.; Peng, H. Chemically programmable and switchable CAR-T therapy. Angew. Chem. Int. Ed. Eng, 2020, 59, 12178-12185.
[5]
Miller, Stephen; Tsuji, Kohei; Burke, Terrence R., Jr.; Schneider, Joel P. Uncoupling the folding-function paradigm of lytic peptides to deliver impermeable inhibitors of intracellular protein-protein interactions. J. Amer. Chem. Soc., 2020, 142, 19950-19955.
[6]
X.Z. Zhao, E.; Kiselev, G.T.; Lountos, W.; Wang, J.E.; Tropea, D.; Needle, T.A.; Hilimire, J.S.; Schneekloth, Jr., D.S.; Waugh, Y. Pommier and; T.R., Burke, Jr. Small molecule microarray identifies inhibitors of tyrosyl-DNA phosphodiesterase 1 that simultaneously access the catalytic pocket and two substrate binding sites. Chem. Sci., 2021, 12, 3876-3884.
[7]
Barski, M.S.; Vanzo, T.; Zhao, X.Z.; Smith, S.J.; Ballandras-Colas, A.; Cronin, N.B.; Pye, V.E.; Hughes, S.H.; Burke, T.R.; Cherepanov, P.; Maertens, G.N. Structural basis for the inhibition of HTLV-1 integration inferred from cryo-EM deltaretroviral intasome structures. Nature Comm., 2021, 12, 4996.
[8]
Hymel, D.; Tsuji, K.; Grant, R. A.; Chingle, R. M.; Kunciw, D. L.; Yaffe, M. B.; Burke, T. R., Jr. Design and synthesis of a new orthogonally protected glutamic acid analog and its use in the preparation of high affinity polo-like kinase 1 polo-box domain-binding peptide macrocycles. Org. Biomol. Chem., 2021, 19, 7843-7854.
[9]
Zhao, X. Z.; Wang, W.; Lountos, G. T.; Tropea, J. E.; Needle, D.; Pommier, Y.; Burke, T. R., Jr. Phosphonic acid-containing inhibitors of tyrosyl-DNA phosphodiesterase 1. Frontiers Chem., 2022. Ahead of Print
[http://dx.doi.org/10.3389/fchem.2022.910953]
[http://dx.doi.org/10.3389/fchem.2022.910953]
[10]
Tsuji, K.; Hymel, D.; Ma, B.; Tamamura, H.; Nussinov, R.; Burke, T. R., Jr. Development of ultra-high affinity bivalent ligands targeting the polo-like kinase RSC Chem. Biol., 2022. Ahead of Print
[http://dx.doi.org/10.1039/d2cb00153e]
[http://dx.doi.org/10.1039/d2cb00153e]
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