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Current Drug Safety

Editor-in-Chief

ISSN (Print): 1574-8863
ISSN (Online): 2212-3911

Research Article

Aluminum Phosphide Poisoning in the North of Iran: A Register-based Research

Author(s): Hamid Mohammadi Kojidi, Mirsaeed Attarchi, Morteza Rahbar-Taramsari*, Alireza Badsar, Niloofar Faraji, Yalda Rastak and Hadi Sedigh Ebrahim-Saraie

Volume 18, Issue 3, 2023

Published on: 07 October, 2022

Page: [323 - 334] Pages: 12

DOI: 10.2174/1574886317666220627112353

Price: $65

Abstract

Background: Aluminum phosphide (ALP) poisoning is considered one of the health care issues in Iran, which is associated with the mortality outcome of patients.

Introduction: According to the ALP poisoning that commonly results in death, we aimed to evaluate the prevalence of ALP pill poisoning by employing register-based research.

Methods: In this descriptive cross-sectional study, all selected patients diagnosed and confirmed with ALP poisoning by a specialist and referred to the poisoning ward from the beginning of April 2016 to the end of October 2017 were enrolled, and data were registered in the Disease Registration System by a technical expert for daily follow-up during hospitalization.

Results: Approximately 12.4% of patients had neurological problems, with the majority having paresis (68.3%). Self-poisoning with the purpose of suicide was documented for 96.2% of cases, with the most common cause being family problems (54.1%). In 97.3% of cases, the method of contact with the toxic substance was oral. Hypotension, cardiac, and respiratory complications were observed in 25.2%, 30.8%, and 25% of the patients, respectively. The most gastrointestinal symptoms were nausea and vomiting (86.7%).

Conclusion: The results indicate that the rate of ALP pill poisoning is relatively high. Suicide is the most important cause of ALP poisoning, which is more common in men under 40 years of age.

Keywords: Poisoning, Aluminium phosphide, Aluminium phosphide pills, Suicide, Neurological problem, Self-poisoning

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