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CNS & Neurological Disorders - Drug Targets

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ISSN (Print): 1871-5273
ISSN (Online): 1996-3181

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Rethinking Catatonia: New Insights from the Autism Spectrum

Author(s): Liliana Dell’Osso, Daniela Toschi, Giulia Amatori* and Camilla Gesi

Volume 22, Issue 4, 2023

Published on: 15 June, 2022

Page: [462 - 465] Pages: 4

DOI: 10.2174/1871527321666220406105844

open access plus

Abstract

Initially conceptualized as a subtype of schizophrenia, catatonia has progressively been recognized to occur in a wide variety of conditions as a kind of final common pathway for many severe mental disorders. There is a significant overlap between the fundamental symptoms of autism spectrum disorder (ASD) and catatonia, and ASD can frequently complicate catatonic states. While provocative, the hypothesis that neuroatypicality may represent the submerged structural piece underlying catatonic states is intriguing. Yet, the multifaced relationship between catatonia and ASD may provide new insights into the etiology and treatment of both disorders.

Keywords: Catatonia, catatonic spectrum, autism spectrum disorder, psychomotor retardation, CNS, DSM-5.

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