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Current Neuropharmacology

Editor-in-Chief

ISSN (Print): 1570-159X
ISSN (Online): 1875-6190

Editorial

Medicinal Chemistry Studies Against Neurodegenerative Diseases

Author(s): Luciana Scotti and Marcus T. Scotti

Volume 20, Issue 5, 2022

Published on: 29 March, 2022

Page: [822 - 823] Pages: 2

DOI: 10.2174/1570159X2005220329113736

[1]
Corsaro, A.; Thellung, S.; Bucciarelli, T.; Scotti, L.; Chiovitti, K.; Villa, V.; D’Arrigo, C.; Aceto, A.; Florio, T. High hydrophobic amino acid exposure is responsible of the neurotoxic effects induced by E200K or D202N disease-related mutations of the human prion protein. Int. J. Biochem. Cell Biol., 2011, 43(3), 372-382.
[http://dx.doi.org/10.1016/j.biocel.2010.11.007]
[2]
de Moura, E.P.; Fernandes, N.D.; Monteiro, A.F.M.; de Medeiros, H.I.R.; Scotti, M.T.; Scotti, L. Machine learning, molecular modeling and Qsar studies of natural products against Alzheimer’s Disease. Curr. Med. Chem., 2021, 28(38), 7808-7829.
[3]
Ishiki, H.M.; Barbosa, J.M.; da Silva, M.S.; Scotti, M.T.; Scotti, L. Computer-aided drug design applied to parkinson targets. Curr. Neuropharmacol., 2018, 16(6), 865-880.
[4]
Lorenzo, V.P.; Alves, M.F.; Scotti, L.; dos Santos, S.G.; Diniz, M.; Scotti, M.T. Computational chemistry study of natural alkaloids and homemade databank to predict inhibitory potential against key enzymes in neurodegenerative diseases. Curr. Top. Med. Chem., 2017, 17(26), 2926-2934.
[5]
Maia, M.D.; Rodrigues, G.C.S.; de Sousa, N.F.; Scotti, M.T.; Scotti, L.; Mendonca, F.J.B. Identification of new targets and the virtual screening of lignans against Alzheimer’s Disease. Oxid. Med. Cell. Longev., 2020, 20203098673
[6]
Mendonca, F.J.B.; Scotti, M.T.; Muratov, E.N.; Scotti, L.; Nayarisseri, A. Natural bioactive products with antioxidant properties useful in neurodegenerative diseases 2020. Oxid. Med. Cell. Longev., 2021, 20216262316
[7]
Mendonca, F.J.B.; Scotti, M.T.; Nayarisseri, A.; Zondegoumba, E.N.T.; Scotti, L. Natural bioactive products with antioxidant properties useful in Neurodegenerative Diseases. Oxid. Med. Cell. Longev., 2019, 20197151780
[8]
Monteiro, A.F.M.; Viana, J.D.; Nayarisseri, A.; Zondegoumba, E.N.; Mendonca, F.J.B.; Scotti, M.T.; Scotti, L. Computational studies applied to flavonoids against Alzheimer’s and Parkinson’s Diseases. Oxid. Med. Cell. Longev., 2018, 20187912765
[9]
Ribeiro, F.F.; Mendonca, F.J.B.; Ghasemi, J.B.; Ishiki, H.M.; Scotti, M.T.; Scotti, L. Docking of Natural Products Against Neurodegenerative Diseases: General Concepts. Comb. Chem. High Throughput Screen., 2018, 21(3), 152-160.
[10]
Scotti, L.; Scotti, M.T.; Pasqualoto, K.F.M.; Bolzani, V.D.; Ferreira, E.I. Molecular physicochemical parameters predicting antioxidant activity of Brazilian natural products. Revista Brasileira De Farmacognosia-Brazil. J. Pharmacol., 2009, 19(4), 908-913.
[11]
Sousa, N.F.; Scotti, L.; Moura, É.P.; Maia, M.S.; Soares, G.C.S.; Medeiros, H.I.R.; Lopes, S.M.; Scotti, M.T. Computer aided drug design methodologies with natural products in the drug research against Alzheimer’s Disease. Curr. Neuropharmacol., 2022, 20(5), 857-885.
[12]
Fakhri, S.; Moradi, S.Z.; Khan, H. Phytochemicals targeting oxidative stress, interconnected neuroinflammatory and neuroapoptotic pathways following radiation. Curr. Neuropharmacol., 2022, 20(5), 836-856.
[13]
Kumar, R.; Harilal, S.; Parambi, D.G.T.; Kanthlal, S.K.; Rahman, M.A.; Alexiou, A.; Batiha, G.E-S.; Mathew, B. The role of mitochondrial Genes in neurodegenerative disorders. Curr. Neuropharmacol., 2022, 20(5), 824-835.

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