Circumstantial Insights into the Potential of Traditional Chinese Medicinal Plants as
a Therapeutic Approach in Rheumatoid Arthritis

Twinkle      Sharma; Parth      Sharma; Parteek      Chandel; Sukhbir      Singh; Neelam      Sharma; Tanveer      Naved; Saurabh      Bhatia; Ahmed      Al-Harrasi; Simona      Bungau; Tapan      Behl

doi:10.2174/1381612828666220324124720

Abstract

The advanced era has invited a plethora of chronic and autoimmune infirmities unmistakably dominated by rheumatoid arthritis, occurring because of equivocal causes, including ecological factors, genetic variations, etc. Unfortunately, it is winning pretty much in every stratum of the society in the undefined age group of the population. Engineered drugs are accessible for the treatment; however, they do experience adverse effects as the treatment requires a prolonged duration worsened by noncompliance. To overwhelm it, certain pharmacological and molecular pathways are explored in the wake of Chinese herbs that prompted the prevention of this deteriorating autoimmune disease. The alcoholic extracts and decoctions are procured from Chinese herbs, such as Paeonia lactiflora, Glycyrrhiza uralensis, Tripterygium wilfordii, etc., which have been proved to manifest constructive pharmacological actions. The activities that were exhibited by extracts are significantly innocuous, non-toxic, and potent to fix the affliction in contrast with the chemosynthetic drugs. Therefore, these Chinese herbs bring forth potent anti-inflammatory, immune-suppressing, anti-nociceptive, anti-neovascularizing, free radical scavenging activities, and various other benefits to withstand several pathological events that usually endure infirmity. It can be abridged that Chinese herbs possess assorted and selective therapeutic properties with profound safety and viability to treat this rheumatic disorder. Thus, this review aims to shed light on naturally originated treatment that is pertinent to providing invulnerable therapy exonerating from adverse effects by restraining joint deformities, production of auto-antibodies, and inflammation.

Keywords: Anti-inflammatory, anti-neovascularising, anti-nociceptive, Glycyrrhiza uralensis, Paeonia lactiflora, Sinomenium acutum, Tripterygium wilfordii.

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DOI https://dx.doi.org/10.2174/1381612828666220324124720	Print ISSN 1381-6128
Publisher Name Bentham Science Publisher	Online ISSN 1873-4286

Current Pharmaceutical Design

Circumstantial Insights into the Potential of Traditional Chinese Medicinal Plants as a Therapeutic Approach in Rheumatoid Arthritis

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