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Cardiovascular & Hematological Disorders-Drug Targets

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ISSN (Print): 1871-529X
ISSN (Online): 2212-4063

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Case Report

Acute Myocardial Infarction in Hemophilia A with HIV and Hyperhomocysteinemia- A Rare Case Report

Author(s): Arjun Kachhwaha, Amit Kumar Rohila*, Swapnil Tripathi, Durga Shankar Meena, Satyendra Khichar and Deepak Kumar

Volume 22, Issue 1, 2022

Published on: 14 April, 2022

Page: [3 - 5] Pages: 3

DOI: 10.2174/1871529X22666220126122458

Price: $65

Abstract

Background: Patients with hemophilia have a hypocoagulable state and less chances of thrombus formation. Therefore, they are expected to have a lower cardiovascular mortality than the general population. The lower cardiovascular mortality can be explained by less chances of thrombus formation due to hypocoagulability.

Case Presentation: Here, we present a case of a 42-year-old male patient who presented with severe chest pain radiating to the back for 4 days. ECG was suggestive of recent acute anteroseptal myocardial infarction. There was a history of receiving intravenous recombinant factor VIII, 1 hour prior to the onset of chest pain for knee joint swelling. The occurrence of acute coronary syndromes in patients with hemophilia A is uncommon and rarely reported.

Conclusion: Here, we report a patient with severe hemophilia A who developed acute myocardial infarction after administration of recombinant factor VIII.

Keywords: Acute Myocardial Infarction, cardiovascular mortality, intravenous recombinant factor, hemophilia, HIV Patient, hyperhomocysteinemia.

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