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Current Rheumatology Reviews

Editor-in-Chief

ISSN (Print): 1573-3971
ISSN (Online): 1875-6360

Perspective

Management of a Hot Swollen Joint in the Acute Setting

Author(s): Jamie Sin Ying Ho, Andrew Kailin Zhou*, Caitlyn Tran, Eric Jou, Milind Girish, Azeem Thahir, Shirom Chabra and Hassan Abbas Hussain

Volume 18, Issue 3, 2022

Published on: 07 March, 2022

Page: [173 - 177] Pages: 5

DOI: 10.2174/1573397118666220113114104

Abstract

Background: The presentation of a hot swollen joint is common in the emergency department, general practice, rheumatology and orthopedic clinics. There is a wide set of differential diagnoses for a hot swollen joint, thus making it difficult to diagnose and manage, especially for junior doctors. Initially, it is pertinent to exclude/diagnose medical and surgical emergencies.

Objective: This paper aims to summarize the key indications within the history, examination and investigations in order to quickly and effectively diagnose a hot swollen joint based on the original 2006 management guidelines and the papers discussing other possible indications and management strategies published since then.

Results: Currently, the management of crystal and non-infectious arthropathies is well recognized with little disparity. However, the treatment of infectious arthritis is not concrete, and there are discrepancies in management between doctors.

Conclusion: We have summarized the key indications and provided a diagnostic flow chart to aid with the management of a hot swollen joint.

Keywords: Hot swollen joint, septic arthritis, gout, joint pain, monoarticular arthritis, acute management, crystal arthropathy.

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[1]
Coakley G, Mathews C, Field M, et al. British Society for Rheumatology Standards, Guidelines and Audit Working Group. BSR & BHPR, BOA, RCGP and BSAC guidelines for management of the hot swollen joint in adults. Rheumatology (Oxford) 2006; 45(8): 1039-41.
[http://dx.doi.org/10.1093/rheumatology/kel163a] [PMID: 16829534]
[2]
Chisari E, Yaghmour KM, Peat F, Khan W. Patients presenting with a hot, swollen joint: A single-centre retrospective analysis. Curr Rheumatol Rev 2020; 16(1): 38-42.
[http://dx.doi.org/10.2174/1573397115666190122113659] [PMID: 30666912]
[3]
Ma L, Cranney A, Holroyd-Leduc JM. Acute monoarthritis: What is the cause of my patient’s painful swollen joint? CMAJ 2009; 180(1): 59-65.
[http://dx.doi.org/10.1503/cmaj.080183] [PMID: 19124791]
[4]
Becker JA, Daily JP, Pohlgeers KM. Acute monoarthritis: Diagnosis in adults. Am Fam Physician 2016; 94(10): 810-6.
[PMID: 27929277]
[5]
Margaretten ME, Kohlwes J, Moore D, Bent S. Does this adult patient have septic arthritis? JAMA 2007; 297(13): 1478-88.
[http://dx.doi.org/10.1001/jama.297.13.1478] [PMID: 17405973]
[6]
Mathews CJ, Weston VC, Jones A, Field M, Coakley G. Bacterial septic arthritis in adults. Lancet 2010; 375(9717): 846-55.
[http://dx.doi.org/10.1016/S0140-6736(09)61595-6] [PMID: 20206778]
[7]
Mathews CJ, Coakley G. Septic arthritis: Current diagnostic and therapeutic algorithm. Curr Opin Rheumatol 2008; 20(4): 457-62.
[http://dx.doi.org/10.1097/BOR.0b013e3283036975] [PMID: 18525361]
[8]
Long B, Koyfman A, Gottlieb M. Evaluation and management of septic arthritis and its mimics in the emergency department. West J Emerg Med 2019; 20(2): 331-41.
[http://dx.doi.org/10.5811/westjem.2018.10.40974] [PMID: 30881554]
[9]
Carpenter CR, Schuur JD, Everett WW, Pines JM. Evidence-based diagnostics: Adult septic arthritis. Acad Emerg Med 2011; 18(8): 781-96.
[http://dx.doi.org/10.1111/j.1553-2712.2011.01121.x] [PMID: 21843213]
[10]
Farah Z, Reddy V, Matthews W, Giles I. Poor adherence to guidelines on early management of acute hot swollen joint(s): An evaluation of clinical practice and implications for training. Int J Clin Pract 2015; 69(5): 618-22.
[http://dx.doi.org/10.1111/ijcp.12580] [PMID: 25650874]
[11]
Horowitz DL, Katzap E, Horowitz S, Barilla-LaBarca ML. Approach to septic arthritis. Am Fam Physician 2011; 84(6): 653-60.
[PMID: 21916390]
[12]
Kaandorp CJ, Van Schaardenburg D, Krijnen P, Habbema JD, van de Laar MA. Risk factors for septic arthritis in patients with joint disease. A prospective study. Arthritis Rheum 1995; 38(12): 1819-25.
[http://dx.doi.org/10.1002/art.1780381215] [PMID: 8849354]
[13]
Weston VC, Jones AC, Bradbury N, Fawthrop F, Doherty M. Clinical features and outcome of septic arthritis in a single UK Health District 1982-1991. Ann Rheum Dis 1999; 58(4): 214-9.
[http://dx.doi.org/10.1136/ard.58.4.214] [PMID: 10364899]
[14]
NICE. Recommendations | Lyme disease | Guidance | NICE. Available from:https://www.nice.org.uk/guidance/ng95/chapter/Recommendations#clinical-assessment
[15]
Singh JA, Reddy SG, Kundukulam J. Risk factors for gout and prevention: A systematic review of the literature. Curr Opin Rheumatol 2011; 23(2): 192-202.
[http://dx.doi.org/10.1097/BOR.0b013e3283438e13] [PMID: 21285714]
[16]
Choi HK, Atkinson K, Karlson EW, Willett W, Curhan G. Purine-rich foods, dairy and protein intake, and the risk of gout in men. N Engl J Med 2004; 350(11): 1093-103.
[http://dx.doi.org/10.1056/NEJMoa035700] [PMID: 15014182]
[17]
Mitrovic DR, Stankovic A, Iriarte-Borda O, et al. The prevalence of chondrocalcinosis in the human knee joint. An autopsy survey. J Rheumatol 1988; 15(4): 633-41.
[PMID: 3397973]
[18]
Rynes RI, Merzig EG. Calcium pyrophosphate crystal deposition disease and hyperparathyroidism: A controlled, prospective study. J Rheumatol 1978; 5(4): 460-8.
[PMID: 216803]
[19]
Dymock IW, Hamilton EB, Laws JW, Williams R. Arthropathy of haemochromatosis. Clinical and radiological analysis of 63 patients with iron overload. Ann Rheum Dis 1970; 29(5): 469-76.
[http://dx.doi.org/10.1136/ard.29.5.469] [PMID: 5476674]
[20]
Ramos YF, Bos SD, van der Breggen R, et al. A gain of function mutation in TNFRSF11B encoding osteoprotegerin causes osteoarthritis with chondrocalcinosis. Ann Rheum Dis 2015; 74(9): 1756-62.
[http://dx.doi.org/10.1136/annrheumdis-2013-205149] [PMID: 24743232]
[21]
Punzi L, Calò L, Schiavon F, Pianon M, Rosada M, Todesco S. Chondrocalcinosis is a feature of Gitelman’s variant of Bartter’s syndrome. A new look at the hypomagnesemia associated with calcium pyrophosphate dihydrate crystal deposition disease. Rev Rhum Engl Ed 1998; 65(10): 571-4.
[PMID: 9809361]
[22]
Richette P, Ayoub G, Bardin T, Bouvet S, Orcel P, Badran AM. Hypomagnesemia and chondrocalcinosis in short bowel syndrome. J Rheumatol 2005; 32(12): 2434-6.
[PMID: 16331778]
[23]
Gouveri E, Papanas N. Charcot osteoarthropathy in diabetes: A brief review with an emphasis on clinical practice. World J Diabetes 2011; 2(5): 59-65.
[http://dx.doi.org/10.4239/wjd.v2.i5.59] [PMID: 21691556]
[24]
Reed MJ, Carachi A. Management of the nontraumatic hot swollen joint. Eur J Emerg Med 2012; 19(2): 103-7.
[http://dx.doi.org/10.1097/MEJ.0b013e328348d8f8] [PMID: 21730866]
[25]
Gbejuade H, Elsakka M, Cutler L. How well does synovial fluid gram staining correlate with cultures in native joint infections? Orthop Rev (Pavia) 2019; 11(4): 8156.
[http://dx.doi.org/10.4081/or.2019.8156] [PMID: 31897276]
[26]
Coutlakis PJ, Roberts WN, Wise CM. Another look at synovial fluid leukocytosis and infection. J Clin Rheumatol 2002; 8(2): 67-71.
[http://dx.doi.org/10.1097/00124743-200204000-00001] [PMID: 17041325]
[27]
Kocher MS, Zurakowski D, Kasser JR. Differentiating between septic arthritis and transient synovitis of the hip in children: An evidence-based clinical prediction algorithm. J Bone Joint Surg Am 1999; 81(12): 1662-70.
[http://dx.doi.org/10.2106/00004623-199912000-00002] [PMID: 10608376]
[28]
Nguyen A, Kan JH, Bisset G, Rosenfeld S. Kocher criteria revisited in the era of MRI: How often does the Kocher criteria identify underlying osteomyelitis? J Pediatr Orthop 2017; 37(2): e114-9.
[http://dx.doi.org/10.1097/BPO.0000000000000602] [PMID: 28170361]
[29]
Kocher MS, Mandiga R, Zurakowski D, Barnewolt C, Kasser JR. Validation of a clinical prediction rule for the differentiation between septic arthritis and transient synovitis of the hip in children. J Bone Joint Surg Am 2004; 86(8): 1629-35.
[http://dx.doi.org/10.2106/00004623-200408000-00005] [PMID: 15292409]
[30]
Caird MS, Flynn JM, Leung YL, Millman JE, D’Italia JG, Dormans JP. Factors distinguishing septic arthritis from transient synovitis of the hip in children. A prospective study. J Bone Joint Surg Am 2006; 88(6): 1251-7.
[http://dx.doi.org/10.2106/00004623-200606000-00012] [PMID: 16757758]
[31]
Glazier RH, Dalby DM, Badley EM, et al. Management of common musculoskeletal problems: A survey of Ontario primary care physicians. CMAJ 1998; 158(8): 1037-40. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1229226/
[32]
Weston V, Coakley G. British society for rheumatology (BSR) standards, guidelines and audit working group; British society for antimicrobial chemotherapy; British orthopaedic association; Royal college of general practitioners; British health professionals in rheumatology. Guideline for the management of the hot swollen joint in adults with a particular focus on septic arthritis. J Antimicrob Chemother 2006; 58(3): 492-3.
[http://dx.doi.org/10.1093/jac/dkl295] [PMID: 16857687]
[33]
Teparrukkul P, Nilsakul J, Dunachie S, Limmathurotsakul D. Clinical epidemiology of septic arthritis caused by Burkholderia pseudomallei and other bacterial pathogens in Northeast Thailand. Am J Trop Med Hyg 2017; 97(6): 1695-701.
[http://dx.doi.org/10.4269/ajtmh.17-0288] [PMID: 29016319]
[34]
Odio CM, Ramirez T, Arias G, et al. Double blind, randomized, placebo-controlled study of dexamethasone therapy for hematogenous septic arthritis in children. Pediatr Infect Dis J 2003; 22(10): 883-8.
[http://dx.doi.org/10.1097/01.inf.0000091293.32187.7b] [PMID: 14551489]
[35]
Mathews CJ, Kingsley G, Field M, et al. Management of septic arthritis: A systematic review. Ann Rheum Dis 2007; 66(4): 440-5.
[http://dx.doi.org/10.1136/ard.2006.058909] [PMID: 17223664]
[36]
Sammer DM, Shin AY. Comparison of arthroscopic and open treatment of septic arthritis of the wrist. J Bone Joint Surg Am 2009; 91(6): 1387-93.
[http://dx.doi.org/10.2106/JBJS.H.00630] [PMID: 19487516]
[37]
Stake S, Scully R, Swenson S, et al. Repeat irrigation & debridement for patients with acute septic knee arthritis: Incidence and risk factors. J Clin Orthop Trauma 2020; 11(Suppl 1): S177-83.
[http://dx.doi.org/10.1016/j.jcot.2019.12.006]
[38]
Colston J, Atkins B. Bone and joint infection. Clin Med (Lond) 2018; 18(2): 150-4.
[http://dx.doi.org/10.7861/clinmedicine.18-2-150] [PMID: 29626020]

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