Login Register Cart 0
Generic placeholder image

Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Back
Journal Home About Journal Editorial Board Journal Insight Current Issue Volumes/Issues
Subscribe
Letter Article

Chemical Constituents of the Roots of Astragalus polycladus var. nigrescens

Author(s): Yu Zhang, Han Yang, Xiang Dong, Chao-Jiang Xiao* and Bei Jiang*

Volume 19, Issue 10, 2022

Published on: 02 March, 2022

Page: [814 - 817] Pages: 4

DOI: 10.2174/1570178619666220110140518

Price: $65

conference banner
Abstract

A new cycloartane triterpenoid, 24-acetylcyclocantogenin (1), along with five cycloartane triterpenoids (2-6), eight steroids (7-14) and nine other known compounds (15-23), was obtained from the methanol extract of roots of Astragalus polycladus var. nigrescens. Their structures were elucidated based on extensive spectroscopic analysis (1D and 2D-NMR, MS and IR). They were isolated from A. polycladus var. nigrescens for the first time.

Keywords: Leguminosae, Astragalus polycladus var. nigrescens, root, cycloartane triterpenoids, chemical constituents, 24- acetylcyclocantogenin.

« Previous Next »
Graphical Abstract

[1]
Kunming Institute of Botany. Chinese Academy of Sciences. Flora Yunnanica; Science Press: Beijing, 2006, 10, pp. 717-720.
[2]
Su, H-F.; Shaker, S.; Kuang, Y.; Zhang, M.; Ye, M.; Qiao, X. Med. Res. Rev., 2021, 41(4), 1999-2038.
[http://dx.doi.org/10.1002/med.21785] [PMID: 33464616]
[3]
Salehi, B.; Carneiro, J.N.P.; Rocha, J.E.; Coutinho, H.D.M.; Morais Braga, M.F.B.; Sharifi-Rad, J.; Semwal, P.; Painuli, S.; Moujir, L.M.; De Zarate Machado, V.; Janakiram, S.; Anil Kumar, N.V.; Martorell, M.; Cruz-Martins, N.; El Beyrouthy, M.; Sadaka, C. Phytother. Res., 2021, 35(5), 2445-2476.
[http://dx.doi.org/10.1002/ptr.6974]
[4]
Guo, Z.; Lou, Y.; Kong, M.; Luo, Q.; Liu, Z.; Wu, J. Int. J. Mol. Sci., 2019, 20(6), 1463.
[http://dx.doi.org/10.3390/ijms20061463] [PMID: 30909474]
[5]
Sarraj-Laabidi, A.; Lacaille-Dubois, M-A.; Semmar, N. Phytochem. Rev., 2018, 17(2), 431-452.
[http://dx.doi.org/10.1007/s11101-017-9541-1]
[6]
Qiu, L.; Xiao, C-J.; Shen, Y.; Xu, W.; Liu, X-B.; Dong, X.; Jiang, B. Nat. Prod. Res., 2021, 35(23), 5066-5074.
[http://dx.doi.org/10.1080/14786419.2020.1777410] [PMID: 32524844]
[7]
Jia, M-R.; Li, X-W. Zhongguo Minzuyao Zhiyao; China Medical Science and Technology Press: Beijing, 2005, p. 80.
[8]
Mamedova, R.P.; Isaev, M.I. Chem. Nat. Compd., 2004, 40(4), 303-357.
[http://dx.doi.org/10.1023/B:CONC.0000048246.16075.62]
[9]
Fathiazad, F.; Khosropanah, M.K.; Movafeghi, A. Nat. Prod. Res., 2010, 24(11), 1069-1078.
[http://dx.doi.org/10.1080/14786410902975582] [PMID: 20552530]
[10]
Mamedova, R.P.; Agzamova, M.A.; Isaev, M.I. Chem. Nat. Compd., 2001, 37(6), 533-536.
[http://dx.doi.org/10.1023/A:1014864731925]
[11]
Perrone, A.; Masullo, M.; Bassarello, C.; Bloise, E.; Hamed, A.; Nigro, P.; Pizza, C.; Piacente, S. Tetrahedron, 2008, 64(22), 5061-5071.
[http://dx.doi.org/10.1016/j.tet.2008.03.069]
[12]
İhsan, Ç.; Matej, B.; Guido, J. Z. Naturforsch. C, 2008, 63(11-12), 813-820.
[http://dx.doi.org/10.1515/znc-2008-11-1206] [PMID: 19227828]
[13]
Cho, E.J.; Ji, Y.C.; Lee, K.H.; Lee, S. Hortic. Environ. Biotechnol., 2012, 53(6), 561-564.
[http://dx.doi.org/10.1007/s13580-012-0040-4]
[14]
Xiao, C-J.; Zhou, X-L.; Han, B-Y.; Tian, X-Y.; Sun, J-Z. Nat. Prod. Res. Dev., 2013, 25(3), 333-337.
[15]
Hamdan, D.; El-Readi, M.Z.; Tahrani, A.; Herrmann, F.; Kaufmann, D.; Farrag, N.; El-Shazly, A.; Wink, M. Food Chem., 2011, 127(2), 394-403.
[http://dx.doi.org/10.1016/j.foodchem.2010.12.129] [PMID: 23140678]
[16]
Jiang, P.; Han, B.; Jiang, L.; Li, Y.; Yu, Y.; Xu, H.; Li, Z.; Zhou, D.; Jia, X.; Li, X.; Ye, X. J. Pharm. Biomed. Anal., 2019, 174, 718-727.
[http://dx.doi.org/10.1016/j.jpba.2019.06.048] [PMID: 31295647]
[17]
Xiao, C-J.; Qiu, L.; Xu, W.; Dong, X.; Jiang, B. Chin. Tradit. Herbal Drugs, 2015, 46(1), 22-27.
[18]
Reynolds, W.F.; Mclean, S.; Poplawski, J.; Enriquez, R.G.; Escobar, L.I.; Leon, I. Tetrahedron, 1986, 42(13), 3419-3428.
[http://dx.doi.org/10.1016/S0040-4020(01)87309-9]
[19]
Garcez, F.R.; Garcez, W.S.; Hamerski, L.; Miguita, C.H. Quim. Nova, 2009, 32(2), 407-411.
[http://dx.doi.org/10.1590/S0100-40422009000200026]
[20]
Chen, C.T.; Kuo, J.H.; Ku, C.H.; Weng, S.S.; Liu, C.Y. J. Org. Chem., 2005, 70(4), 1328-1339.
[http://dx.doi.org/10.1021/jo0484878] [PMID: 15704967]
[21]
Otsuka, H.; Qian, Y.; Matsunami, K. Heterocycles, 2010, 80(1), 339-348.
[http://dx.doi.org/10.3987/COM-09-S(S)22]
[22]
Huang, Z.Y.; Huang, B.; Xiao, C.J.; Dong, X.; Yang, L.Y.; Jiang, B. Lishizhen Med. Mater. Med. Res., 2014, 25(2), 286-287.
[23]
Zhao, J-W.; Chen, D-S.; Deng, C-S.; Wang, Q.; Zhu, W.; Lin, L. BMC Complement. Altern. Med., 2017, 17(1), 7.
[http://dx.doi.org/10.1186/s12906-016-1539-5] [PMID: 28056939]
[24]
Su, B-N.; Misico, R.; Park, E.J.; Santarsiero, B.D.; Mesecar, A.D.; Fong, H.H.; Pezzuto, J.M.; Kinghorn, A.D. Tetrahedron, 2002, 58(17), 3453-3466.
[http://dx.doi.org/10.1016/S0040-4020(02)00277-6]

Rights & Permissions Print Cite
Article Metrics
19
1
© 2024 Bentham Science Publishers | Privacy Policy