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Current Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 0929-8673
ISSN (Online): 1875-533X

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Editorial

Osteopontin in CardioMetabolic Medicine: A Risk Stratification Biomarker with Future Therapeutic Implication

Author(s): Federico Carbone* and Fabrizio Montecucco*

Volume 29, Issue 25, 2022

Published on: 25 March, 2022

Page: [4314 - 4316] Pages: 3

DOI: 10.2174/0929867329666211228113716

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Vecchié, A.; Dallegri, F.; Carbone, F.; Bonaventura, A.; Liberale, L.; Portincasa, P.; Frühbeck, G.; Montecucco, F. Obesity phenotypes and their paradoxical association with cardiovascular diseases. Eur. J. Intern. Med., 2018, 48, 6-17.
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[6]
Carbone, F.; Rigamonti, F.; Burger, F.; Roth, A.; Bertolotto, M.; Spinella, G.; Pane, B.; Palombo, D.; Pende, A.; Bonaventura, A.; Lib-erale, L.; Vecchié, A.; Dallegri, F.; Mach, F.; Montecucco, F. Serum levels of osteopontin predict major adverse cardiovascular events in patients with severe carotid artery stenosis. Int. J. Cardiol., 2018, 255, 195-199.
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[7]
Carbone, F.; Dallegri, F.; Montecucco, F.; Poggi, A.; Nobili, F.M.; Cacciapaglia, F.; Afeltra, A.; Moccetti, T.; Colombo, B.M. Serum osteopontin negatively impacts on intima-media thickness in patients with systemic lupus erythematosus. Eur. J. Clin. Invest., 2019, 49(5), e13089.
[http://dx.doi.org/10.1111/eci.13089] [PMID: 30767212]
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Carbone, F.; Bonaventura, A.; Liberale, L.; Paolino, S.; Torre, F.; Dallegri, F.; Montecucco, F.; Cutolo, M. Atherosclerosis in rheumatoid arthritis: Promoters and opponents. Clin. Rev. Allergy Immunol., 2020, 58(1), 1-14.
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Kiefer, F.W.; Zeyda, M.; Gollinger, K.; Pfau, B.; Neuhofer, A.; Weichhart, T.; Säemann, M.D.; Geyeregger, R.; Schlederer, M.; Kenner, L.; Stulnig, T.M. Neutralization of osteopontin inhibits obesity-induced inflammation and insulin resistance. Diabetes, 2010, 59(4), 935-946.
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Honda, M.; Kimura, C.; Uede, T.; Kon, S. Neutralizing antibody against osteopontin attenuates non-alcoholic steatohepatitis in mice. J. Cell Commun. Signal., 2020, 14(2), 223-232.
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Ross, R.; Neeland, I.J.; Yamashita, S.; Shai, I.; Seidell, J.; Magni, P.; Santos, R.D.; Arsenault, B.; Cuevas, A.; Hu, F.B.; Griffin, B.A.; Zambon, A.; Barter, P.; Fruchart, J.C.; Eckel, R.H.; Matsuzawa, Y.; Després, J.P. Waist circumference as a vital sign in clinical practice: A consensus statement from the IAS and ICCR working group on visceral obesity. Nat. Rev. Endocrinol., 2020, 16(3), 177-189.
[http://dx.doi.org/10.1038/s41574-019-0310-7] [PMID: 32020062]

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