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Letters in Organic Chemistry

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ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

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Research Article

Ultrasound-Assisted Synthesis of β-enaminone Derivatives via Tin(IV)- Catalyzed Addition Reaction from β-dicarbonyl Compounds with Nitriles

Author(s): Shuchen Pei, Jinhua Yang, Jieyu Wang, Kangyao Yuan and Ziqiang Li*

Volume 19, Issue 6, 2022

Published on: 13 January, 2022

Page: [498 - 503] Pages: 6

DOI: 10.2174/1570178619666211221141854

Price: $65

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Abstract

An efficient and eco-friendly approach for the synthesis of β-enaminone derivatives is described by adding nitriles with β-dicarbonyl compounds under ultrasound irradiation conditions at room temperature. The scope and limitation of this strategy are also discussed. A variety of substituted amides can be obtained in moderate to good yields. We hope that this protocol for the efficient synthesis of β-enaminones will offer insights into further investigations.

Keywords: Tin, catalysis, β-dicarbonyl compounds, ultrasound irradiation, enaminone, synthesis.

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