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Current Molecular Medicine

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ISSN (Print): 1566-5240
ISSN (Online): 1875-5666

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Review Article

Metabolomics Work Flow and Analytics in Systems Biology

Author(s): Sanoj Chacko*, Yumna B. Haseeb and Sohaib Haseeb

Volume 22, Issue 10, 2022

Published on: 31 January, 2022

Page: [870 - 881] Pages: 12

DOI: 10.2174/1566524022666211217102105

Price: $65

Abstract

Metabolomics is an omics approach of systems biology that involves the development and assessment of large-scale, comprehensive biochemical analysis tools for metabolites in biological systems. This review describes the metabolomics workflow and provides an overview of current analytic tools used for the quantification of metabolic profiles. We explain analytic tools such as mass spectrometry (MS), nuclear magnetic resonance (NMR) spectroscopy, ionization techniques, and approaches for data extraction and analysis.

Keywords: Biomarker, liquid chromatography, metabolomics, mass spectrometry, NMR spectroscopy, proteome.

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