Generic placeholder image

Recent Advances in Anti-Infective Drug Discovery

Editor-in-Chief

ISSN (Print): 2772-4344
ISSN (Online): 2772-4352

Perspective

The Spectrum of Biochemical Alterations with Molecular and Serological Biomarkers in the Diagnosis of COVID-19: Searching for Novel One to Identify Disease Earlier with Better Prognosis and Drug Discovery

Author(s): Suman Kumar Ray and Sukhes Mukherjee*

Volume 16, Issue 3, 2021

Published on: 20 December, 2021

Page: [179 - 181] Pages: 3

DOI: 10.2174/2772434416666211122112743

Abstract

Clinical and laboratory predictors of progression to serious and deadly forms are crucial in the fight against COVID-19, which has now become a worldwide pandemic. The clinical laboratory's vital role in today's crises has never been more obvious. These subjective clinical signals can be perceived more confidently during an examination with the help of biomarkers. To best combat present and future pandemics, global unity on test access is required, as well as infection prevention and diagnostic measures that are tightly linked.

Keywords: COVID-19, pandemic, SARS-CoV-2 antigens, biomarkers, drug discovery, patent.

[1]
Phua J, Weng L, Ling L, et al. Intensive care management of coronavirus disease 2019 (COVID-19): challenges and recommendations. Lancet Respir Med 2020; 8(5): 506-17.
[http://dx.doi.org/10.1016/S2213-2600(20)30161-2] [PMID: 32272080]
[2]
Vandenberg O, Martiny D, Rochas O, van Belkum A, Kozlakidis Z. Considerations for diagnostic COVID-19 tests. Nat Rev Microbiol 2021; 19(3): 171-83.
[http://dx.doi.org/10.1038/s41579-020-00461-z] [PMID: 33057203]
[3]
Malik P, Patel U, Mehta D, et al. Biomarkers and outcomes of COVID-19 hospitalisations: systematic review and meta-analysis. BMJ Evid Based Med 2021; 26(3): 107-8.
[http://dx.doi.org/10.1136/bmjebm-2020-111536] [PMID: 32934000]
[4]
Kermali M, Khalsa RK, Pillai K, Ismail Z, Harky A. The role of biomarkers in diagnosis of COVID-19 - A systematic review. Life Sci 2020; 254: 117788.
[http://dx.doi.org/10.1016/j.lfs.2020.117788] [PMID: 32475810]
[5]
Faustini SE, Jossi SE, Perez-Toledo M, et al. Detection of antibodies to the SARS-CoV-2 spike glycoprotein in both serum and saliva enhances detection of infection. medRxiv 2020; [pre print article].
[http://dx.doi.org/10.1101/2020.06.16.20133025]
[6]
Ray SK, Mukherjee S. Understanding the role of corona virus based on current scientific evidence - a review with emerging importance in pandemic. Recent Pat Antiinfect Drug Discov 2020; 15(2): 89-103.
[http://dx.doi.org/10.2174/1574891X15999200918144833] [PMID: 32957894]
[7]
Qian X, Ren R, Wang Y, et al. Fighting against the common enemy of COVID-19: A practice of building a community with a shared future for mankind. Infect Dis Poverty 2020; 9(1): 34.
[http://dx.doi.org/10.1186/s40249-020-00650-1] [PMID: 32264957]
[8]
Liu C, Zhou Q, Li Y, et al. Research and development on therapeutic agents and vaccines for covid-19 and related human coronavirus diseases. ACS Cent Sci 2020; 6(3): 315-31.
[http://dx.doi.org/10.1021/acscentsci.0c00272] [PMID: 32226821]

© 2024 Bentham Science Publishers | Privacy Policy