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当代阿耳茨海默病研究

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ISSN (Print): 1567-2050
ISSN (Online): 1875-5828

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Research Article

体力劳动和锻炼可降低老年人认知障碍的风险：一项基于人群的纵向研究

卷 18, 期 8, 2021

发表于: 17 November, 2021

页: [638 - 645] 页: 8

弟呕挨: 10.2174/1567205018666211118100451

价格: $65

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摘要

背景：体力劳动对生活在农村地区的中国老年人认知障碍风险的独立影响仍有待阐明。 目的：我们旨在确定体力劳动和体育锻炼是否可以降低认知障碍的风险。 方法：我们在 2 年的随访期内收集了 7,000 名无认知障碍（年龄≥60 岁）的永久居民的数据。我们使用中文版的简易精神状态检查（MMSE）来评估认知功能。我们进行了多变量 Cox 回归分析，以计算调整后的风险比 (HR) 和 95% 置信区间 (%95 CI)，作为衡量体力工作/锻炼与认知障碍之间关联的指标，同时控制潜在的混杂因素。 结果：在 1.93 年的中位随访期内，7,000 名参与者中有 1,224 名（17.5%）出现认知障碍，总发病率为 97.69/1000 人年。在对潜在的混杂因素进行调整后，参加体育锻炼（HR：0.51；95% CI：0.43-0.60）或体育锻炼（HR：0.53；95% CI：0.44-0.65）与认知障碍风险降低相关。分层分析表明体力工作和锻炼之间的相加和相乘的相互作用。农业工作（HR：0.46；95% CI：0.38-0.55）、步行/太极拳（HR：0.54；95% CI：0.44-0.67）和快走/秧歌（HR：0.57；95% CI：0.33- 0.97）对认知障碍有显着的保护作用。 结论：体力劳动和锻炼都可以降低老年人认知障碍的风险。建议进行合理类型和适当强度的体力活动，以预防或延缓认知障碍的进展。

关键词: 身体活动、认知障碍、纵向研究、风险比、老年人、衰老。

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