Abstract
Enantiomerically pure α-amino ketones are of great importance in natural product synthesis and pharmacological research. However no review concerning their synthesis and applications has been published. Therefore, this review is intended to highlight the above compounds, detailing the available methodologies to prepare enantiopure α-amino ketones in the first part and some synthetic application in the second.
Keywords: organolithium reagents, amino ketones, Weinreb amides, chemical transformations, Reduction, Glycinamides
Current Organic Chemistry
Title: Synthesis and Synthetic Applications of α-Amino Ketones Derived from Natural α-Amino Acids
Volume: 12 Issue: 7
Author(s): Jose M. Concellon and Humberto Rodriguez-Solla
Affiliation:
Keywords: organolithium reagents, amino ketones, Weinreb amides, chemical transformations, Reduction, Glycinamides
Abstract: Enantiomerically pure α-amino ketones are of great importance in natural product synthesis and pharmacological research. However no review concerning their synthesis and applications has been published. Therefore, this review is intended to highlight the above compounds, detailing the available methodologies to prepare enantiopure α-amino ketones in the first part and some synthetic application in the second.
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Cite this article as:
Concellon M. Jose and Rodriguez-Solla Humberto, Synthesis and Synthetic Applications of α-Amino Ketones Derived from Natural α-Amino Acids, Current Organic Chemistry 2008; 12 (7) . https://dx.doi.org/10.2174/138527208784245996
DOI https://dx.doi.org/10.2174/138527208784245996 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
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