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Current Pediatric Reviews

Editor-in-Chief

ISSN (Print): 1573-3963
ISSN (Online): 1875-6336

Review Article

Coronavirus Disease 2019 (COVID-19) and Pregnancy: A Narrative Review

Author(s): Mandana Zafari*, Mohammad Taha Saadati Rad and Fatemeh Mohseni

Volume 18, Issue 2, 2022

Published on: 07 March, 2022

Page: [97 - 102] Pages: 6

DOI: 10.2174/1573396317666210920152541

Price: $65

Abstract

A novel viral respiratory disease caused by severe acute respiratory syndrome, coronavirus 2 (SARS-COV-2), is responsible for a pandemic situation in the world. Pregnant women are susceptible to this virus due to physiologic changes in the immunologic system. The risk of some adverse pregnancy outcomes, such as death, stillbirth, preeclampsia, and intrauterine fetal distress, may increase in infected pregnant women. Infected women should be isolated and investigated, and they should admit to a designated hospital with adequate facilities and multi-disciplinary expertise to manage them. Furthermore, the chances of adverse neonatal complications, such as small for gestational age, large for gestational age, shortness of breath, thrombocytopenia with abnormal liver function, rapid heart rate, vomiting, and pneumothorax, may increase in an affected neonate. This study reviews the problems and guidelines of covid-19 in pregnancy.

Keywords: COVID-19, pregnancy, pandemic, childbirth, delivery, women.

[1]
Xia J, Tong J, Liu M, Shen Y, Guo D. Evaluation of coronavirus in tears and conjunctival secretions of patients with SARS-CoV-2 infection. J Med Virol 2020; 92(6): 589-94.
[http://dx.doi.org/10.1002/jmv.25725] [PMID: 32100876]
[2]
Han Y, Yang H. The transmission and diagnosis of 2019 novel coronavirus infection disease (COVID-19): A Chinese perspective. J Med Virol 2020; 92(6): 639-44.
[http://dx.doi.org/10.1002/jmv.25749] [PMID: 32141619]
[3]
Liang H, Acharya G. Novel corona virus disease (COVID-19) in pregnancy: What clinical recommendations to follow? Acta Obstet Gynecol Scand 2020; 99(4): 439-42.
[http://dx.doi.org/10.1111/aogs.13836] [PMID: 32141062]
[4]
Chen Y, Peng H, Wang L, et al. Infants born to mothers with a new coronavirus (COVID-19). Front Pediatr 2020; 8: 104.
[http://dx.doi.org/10.3389/fped.2020.00104] [PMID: 32266184]
[5]
Yang J, Zheng Y, Gou X, Pu K, Chen Z, Guo Q, et al. Prevalence of comorbidities in the novel Wuhan coronavirus (COVID-19) infection: a systematic review and meta-analysis. Int J Infect Dis 2020; 94: 91-5.
[http://dx.doi.org/10.1016/j.ijid.2020.03.017]
[6]
Sahu KK, Lal A, Mishra AK. COVID-2019 and pregnancy: A plea for transparent reporting of all cases. Acta Obstet Gynecol Scand 2020; 99(7): 951.
[http://dx.doi.org/10.1111/aogs.13850] [PMID: 32191350]
[7]
Schwartz DA, Graham AL. Potential maternal and infant outcomes from (Wuhan) coronavirus 2019-nCoV infecting pregnant women: lessons from SARS, MERS, and other human coronavirus infections. Viruses 2020; 12(2): 194.
[http://dx.doi.org/10.3390/v12020194] [PMID: 32050635]
[8]
Control CfD, prevention. Frequently asked questions and answers: Coronavirus diseases-2019 (COVID-19) and children. 2020. Available from: www.cdc.gov/coronavirus/2019-ncov
[9]
Englund JA, Chu HY. Respiratory virus infection during pregnancy: Does it matter? J Infec Dis 2018; 218(4): 512-55.
[10]
Mullins E, Evans D, Viner RM, O’Brien P, Morris E. Coronavirus in pregnancy and delivery: rapid review. Ultrasound Obstet Gynecol 2020; 55(5): 586-92.
[http://dx.doi.org/10.1002/uog.22014] [PMID: 32180292]
[11]
Assiri A, Abedi GR, Al Masri M, Bin Saeed A, Gerber SI, Watson JT. Middle East respiratory syndrome coronavirus infection during pregnancy: a report of 5 cases from Saudi Arabia. Clin Infect Dis 2016; 63(7): 951-3.
[http://dx.doi.org/10.1093/cid/ciw412] [PMID: 27358348]
[12]
Iwata-Yoshikawa N, Fukushi S, Fukuma A, et al. No susceptibility of neonatal and adult rats against the Middle East respiratory syndrome coronavirus. Japanese J Infect Dis 2016; 2015: 589.
[13]
Alhakeem RF, Midgley CM, Assiri AM, et al. Exposures among MERS case-patients, Saudi Arabia, January–February 2016. Emerg Infect Dis 2016; 22(11): 2020-2.
[14]
Racelis S, de los Reyes VC, Sucaldito MN, Deveraturda I, Roca JB, Tayag E. Contact tracing the first Middle East respiratory syndrome case in the Philippines, February 2015. Western Pac Surveill Response J 2015; 6(3): 3-7.
[http://dx.doi.org/10.5365/wpsar.2015.6.2.012] [PMID: 26668760]
[15]
Alserehi H, Wali G, Alshukairi A, Alraddadi B. Impact of middle east respiratory syndrome coronavirus (MERS-CoV) on pregnancy and perinatal outcome. BMC Infect Dis 2016; 16(1): 105.
[http://dx.doi.org/10.1186/s12879-016-1437-y] [PMID: 26936356]
[16]
Jeong SY, Sung SI, Sung J-H, et al. MERS-CoV infection in a pregnant woman in Korea. J Korean Med Sci 2017; 32(10): 1717-20.
[http://dx.doi.org/10.3346/jkms.2017.32.10.1717] [PMID: 28875620]
[17]
Khan S, Peng L, Siddique R, et al. Impact of COVID-19 infection on pregnancy outcomes and the risk of maternal-to-neonatal intrapartum transmission of COVID-19 during natural birth. Infect Control Hosp Epidemiol 2020; 41(6): 748-50.
[http://dx.doi.org/10.1017/ice.2020.84] [PMID: 32279693]
[18]
Payne DC, Iblan I, Alqasrawi S, et al. Stillbirth during infection with Middle East respiratory syndrome coronavirus. J Infect Dis 2014; 209(12): 1870-2.
[http://dx.doi.org/10.1093/infdis/jiu068] [PMID: 24474813]
[19]
Qiao J. What are the risks of COVID-19 infection in pregnant women? Lancet 2020; 395(10226): 760-2.
[http://dx.doi.org/10.1016/S0140-6736(20)30365-2] [PMID: 32151334]
[20]
Rasmussen SA, Smulian JC, Lednicky JA, Wen TS, Jamieson DJ. Coronavirus disease 2019 (COVID-19) and pregnancy: what obstetricians need to know. Am J Obstet Gynecol 2020; 222(5): 415-26.
[http://dx.doi.org/10.1016/j.ajog.2020.02.017] [PMID: 32105680]
[21]
Schwartz DA. An analysis of 38 pregnant women with COVID-19, their newborn infants, and maternal-fetal transmission of SARS-CoV-2: maternal coronavirus infections and pregnancy outcomes. Arch Pathol Lab Med 2020; 144(7): 799-805.
[http://dx.doi.org/10.5858/arpa.2020-0901-SA] [PMID: 32180426]
[22]
Uddin SMI, Englund JA, Kuypers JY, et al. Burden and risk factors for coronavirus infections in infants in rural Nepal. Clin Infect Dis 2018; 67(10): 1507-14.
[http://dx.doi.org/10.1093/cid/ciy317] [PMID: 29668900]
[23]
Wang X, Zhou Z, Zhang J, Zhu F, Tang Y, Shen X. A case of 2019 Novel Coronavirus in a pregnant woman with preterm delivery. Clin Infect Dis 2020; 71(15): 844-6.
[http://dx.doi.org/10.1093/cid/ciaa200] [PMID: 32119083]
[24]
Li N, Han L, Peng M, Lv Y, Ouyang Y, Liu K, et al. Maternal and neonatal outcomes of pregnant women with COVID-19 pneumonia: a case-control study. Clin Infect Dis 2020; 71(16): 2035-41.
[PMID: 32249918]
[25]
Mullins E, Evans D, Viner R, O’Brien P, Morris E. Coronavirus in pregnancy and delivery: rapid review and expert consensus. medRxiv 2020.
[http://dx.doi.org/10.1101/2020.03.06.20032144]
[26]
Vasylyeva O. Pregnancy and COVID-19, a brief review. Int J Integr Pediatr Environ Med 2020; 5(1): 8-13.
[27]
Liu W, Wang Q, Zhang Q, Chen L, Chen J, Zhang B, et al. Coronavirus disease 2019 (COVID-19) during pregnancy: a case series. 2020; 202002.0373.v1.
[28]
Rothan HA, Byrareddy SN. The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak. J Autoimmun 2020; 109: 102433.
[http://dx.doi.org/10.1016/j.jaut.2020.102433] [PMID: 32113704]
[29]
Liu Y, Chen H, Tang K, Guo Y. Withdrawn: Clinical manifestations and outcome of SARS-CoV-2 infection during pregnancy. J Infect 2020; S0163-4453(20): 30109-2.
[http://dx.doi.org/10.1016/j.jinf.2020.02.028] [PMID: 32145216]
[30]
Sohrabi C, Alsafi Z, O’Neill N, Khan M, Kerwan A, Al-Jabir A, et al. World Health Organization declares global emergency: A review of the 2019 novel coronavirus (COVID-19). Int J Surg 2020; 76: 71-76.
[http://dx.doi.org/10.1016/j.ijsu.2020.02.034]
[31]
Ng M-Y, Lee EYP, Yang J, et al. Imaging profile of the COVID-19 infection: radiologic findings and literature review. Radiol Cardiothorac Imaging 2020; 2(1): e200034.
[http://dx.doi.org/10.1148/ryct.2020200034] [PMID: 33778547]
[32]
Saad AF, Chappell L, Saade GR, Pacheco LD. Corticosteroids in the management of pregnant patients with coronavirus disease (COVID-19). Obstet Gynecol 2020; 136(4): 823-6.
[http://dx.doi.org/10.1097/AOG.0000000000004103] [PMID: 32769659]
[33]
D’Souza R, Ashraf R, Rowe H, et al. Pregnancy and COVID-19: pharmacologic considerations. Ultrasound Obstet Gynecol 2021; 57(2): 195-203.
[http://dx.doi.org/10.1002/uog.23116] [PMID: 32959455]
[34]
Barnes GD, Burnett A, Allen A, et al. Thromboembolism and anticoagulant therapy during the COVID-19 pandemic: interim clinical guidance from the anticoagulation forum. J Thromb Thrombolysis 2020; 50(1): 72-81.
[http://dx.doi.org/10.1007/s11239-020-02138-z] [PMID: 32440883]
[35]
Poon LC, Yang H, Lee JCS, et al. ISUOG interim guidance on 2019 novel coronavirus infection during pregnancy and puerperium: information for healthcare professionals. Ultrasound Obstet Gynecol 2020; 55(5): 700-8.
[http://dx.doi.org/10.1002/uog.22013] [PMID: 32160345]
[36]
Yang H, Wang C, Poon LC. Novel coronavirus infection and pregnancy. Ultrasound Obstet Gynecol 2020; 55(4): 435-7.
[http://dx.doi.org/10.1002/uog.22006] [PMID: 32134165]
[37]
Hong H, Wang Y, Chung H-T, Chen C-J. Clinical characteristics of novel coronavirus disease 2019 (COVID-19) in newborns, infants and children. Pediatr Neonatol 2020; 61(2): 131-2.
[http://dx.doi.org/10.1016/j.pedneo.2020.03.001] [PMID: 32199864]
[38]
Yang P, Liu P, Li D, Zhao D. Corona virus disease 2019, a growing threat to children? J Infect 2020; 80(6): 671-93.
[http://dx.doi.org/10.1016/j.jinf.2020.02.024] [PMID: 32142929]
[39]
Zhu H, Wang L, Fang C, et al. Clinical analysis of 10 neonates born to mothers with 2019-nCoV pneumonia. Transl Pediatr 2020; 9(1): 51-60.
[http://dx.doi.org/10.21037/tp.2020.02.06] [PMID: 32154135]
[40]
Organization WH. Clinical management of severe acute respiratory infection (SARI) when COVID-19 disease is suspected: interim guidance, 13 March 2020.World Health Organization 2020.
[41]
Guery B, Poissy J, el Mansouf L, et al. Clinical features and viral diagnosis of two cases of infection with Middle East Respiratory Syndrome coronavirus: a report of nosocomial transmission. Lancet 2013; 381(9885): 2265-72.
[http://dx.doi.org/10.1016/S0140-6736(13)60982-4] [PMID: 23727167]
[42]
Fisher D, Heymann DQ. Q&A: the novel coronavirus outbreak causing COVID-19. BMC Med 2020; 18(1): 57.
[http://dx.doi.org/10.1186/s12916-020-01533-w] [PMID: 31898501]
[43]
Barrero-Castillero A, Beam KS, Bernardini LB, et al. COVID-19: neonatal-perinatal perspectives. J Perinatol 2021; 41(5): 940-51.
[PMID: 33293665]
[44]
Saeedi M, Sangsari R, Mirnia K. COVID-19 in neonates: A review. Iran J Pediatr 2021; 31(1): 3104423.
[http://dx.doi.org/10.5812/ijp.104423]

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