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Current Pharmaceutical Analysis

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ISSN (Print): 1573-4129
ISSN (Online): 1875-676X

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Mini-Review Article

Mini-Review on Bioanalytical Estimation of Brinzolamide

Author(s): Ajay B. Madrewar, Ashwini Deshpande and Sankha Bhattacharya*

Volume 18, Issue 3, 2022

Published on: 12 August, 2021

Page: [265 - 272] Pages: 8

DOI: 10.2174/1573412917666210812103414

Price: $65

Abstract

Abstract: Brinzolamide is a treatment option for glaucoma. As glaucoma is the third leading cause of blindness, there is a need for analytical methods to obtain an effective drug with great precision and accuracy. Even if brinzolamide is official in IP and USP, different analytical methods still need to be brought in one place, which would help attain better results and easy comparison for other analysis specifications and procedures. This review helps to understand and gather different analysis techniques or biological fluid techniques of brinzolamide in a dosage form. These techniques include UV spectroscopy, HPLC, LC-MS, and TLC densitometry.

Keywords: Brinzolamide, glaucoma, analytical method, UV, HPLC, LC-MS.

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Graphical Abstract

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