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Current Molecular Medicine

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ISSN (Print): 1566-5240
ISSN (Online): 1875-5666

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Review Article

Pharmacodynamic Stance of Phytoconstituents as a Gastric Ulcer Protective Mechanism: An Overview

Author(s): Manish Pal Singh*, Viney Chawla, Darpan Kaushik, Pooja A Chawla and Siddhraj Singh Sisodia

Volume 22, Issue 5, 2022

Published on: 06 August, 2021

Page: [431 - 441] Pages: 11

DOI: 10.2174/1566524021666210806161835

Price: $65

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Abstract

Various traditional herbal plants have been associated with unique pharmacological actions. Natural parts as well as processed plant parts are known to possess gastro-protective and gastro- mucosal healing property. Motive of this review analysis is to explain the gastro-protective and gastro-mucosal healing property of different herbal plants and their constituents indigenous to various regions of the globe and elucidate mechanisms of the healing by their metabolic extracts. Moreover, an attempt shall be made to explicate the possible molecular pharmacological targets responsible for healing gastric ulcer activity. A thorough survey of literature has been carried out from various scientific resources and using keywords like peptic ulcer mechanism, gastro-protective agents, gastro-mucosal healing property, natural and processed herbal drugs preventing peptic ulcers. This article will present a running commentary on the prospects and potential of herbal plants exhibiting gastroprotective activity and gastro-mucosal healing property.

Keywords: Gastric ulcer, gastroprotective, peptic ulcer, phytoconstituents, gastric mucus cell, cytoprotective.

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