Abstract
A green and efficient method for the synthesis of 2-arylimidazo [1, 2-a] pyridine (3) and benzimidazole (8) derivatives has been developed using plant extracts. The different plant part extracts of Terminalia chebula, Punica granatum, and Aegle marmelos have been studied. The aqueous fruit extract of Terminalia chebula gave better results. The synthetic method has been optimized with respect to plant extract quantity, pH of the reaction, and yield. The developed protocol showed several advantages like mild reaction conditions, short reaction time, high yield, and reduced environmental impact.
Keywords: Benzimidazole, 2-arylimidazo [1, 2-a] pyridine, plant extracts, green synthesis, Terminalia chebula, Punica granatum, Aegle marmelos.
Graphical Abstract
Letters in Organic Chemistry
Title:Plant Extract-Assisted Green Synthesis of 2-Arylimidazo [1,2-A] Pyridine and Benzimidazole Derivatives
Volume: 18 Issue: 12
Author(s): Babita Veer and Ram Singh*
Affiliation:
- Department of Applied Chemistry, Delhi Technological University, Delhi 110042,India
Keywords: Benzimidazole, 2-arylimidazo [1, 2-a] pyridine, plant extracts, green synthesis, Terminalia chebula, Punica granatum, Aegle marmelos.
Abstract: A green and efficient method for the synthesis of 2-arylimidazo [1, 2-a] pyridine (3) and benzimidazole (8) derivatives has been developed using plant extracts. The different plant part extracts of Terminalia chebula, Punica granatum, and Aegle marmelos have been studied. The aqueous fruit extract of Terminalia chebula gave better results. The synthetic method has been optimized with respect to plant extract quantity, pH of the reaction, and yield. The developed protocol showed several advantages like mild reaction conditions, short reaction time, high yield, and reduced environmental impact.
Export Options
About this article
Cite this article as:
Veer Babita and Singh Ram *, Plant Extract-Assisted Green Synthesis of 2-Arylimidazo [1,2-A] Pyridine and Benzimidazole Derivatives, Letters in Organic Chemistry 2021; 18 (12) . https://dx.doi.org/10.2174/1570178618666210805103211
DOI https://dx.doi.org/10.2174/1570178618666210805103211 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |

- Author Guidelines
- Bentham Author Support Services (BASS)
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers