Plant Extract-Assisted Green Synthesis of 2-Arylimidazo [1,2-A] Pyridine and Benzimidazole Derivatives

Title:Plant Extract-Assisted Green Synthesis of 2-Arylimidazo [1,2-A] Pyridine and Benzimidazole Derivatives

Volume: 18 Issue: 12

Author(s): Babita Veer and Ram Singh*

Affiliation:

• Department of Applied Chemistry, Delhi Technological University, Delhi 110042,India

Keywords: Benzimidazole, 2-arylimidazo [1, 2-a] pyridine, plant extracts, green synthesis, Terminalia chebula, Punica granatum, Aegle marmelos.

Abstract: A green and efficient method for the synthesis of 2-arylimidazo [1, 2-a] pyridine (3) and benzimidazole (8) derivatives has been developed using plant extracts. The different plant part extracts of Terminalia chebula, Punica granatum, and Aegle marmelos have been studied. The aqueous fruit extract of Terminalia chebula gave better results. The synthetic method has been optimized with respect to plant extract quantity, pH of the reaction, and yield. The developed protocol showed several advantages like mild reaction conditions, short reaction time, high yield, and reduced environmental impact.

Cite this article as:

Veer Babita and Singh Ram *, Plant Extract-Assisted Green Synthesis of 2-Arylimidazo [1,2-A] Pyridine and Benzimidazole Derivatives, Letters in Organic Chemistry 2021; 18 (12) . https://dx.doi.org/10.2174/1570178618666210805103211