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当代阿耳茨海默病研究

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ISSN (Print): 1567-2050
ISSN (Online): 1875-5828

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Research Article

老年人认知纵向发展过程中的风险评估：一个基于社区的贝叶斯网络模型

卷 18, 期 3, 2021

发表于: 23 September, 2021

页: [232 - 242] 页: 11

弟呕挨: 10.2174/1567205018666210608110329

价格: $65

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摘要

背景：认知功能障碍，特别是阿尔茨海默病(AD)，严重影响老年人的健康和生活质量。早期发现可以预防和减缓认知能力下降。 目的：本研究旨在评估社会人口统计学变量、生活方式和身体特征在AD进展过程中认知能力下降中的作用，并分析疾病的可能原因和预测阶段。 方法：通过分析301名受试者的数据包括正常老年人和轻度认知障碍(MCI)或广告从6个社区，太原，我们确定影响因素在逻辑回归模型(LR)，然后评估变量和认知之间的关联使用贝叶斯网络(BNs)模型。 结果：LR结果显示，年龄、性别、家庭状况、受教育程度、收入、性格、抑郁、高血压、病史、体育锻炼、阅读、饮酒和工作状况与认知能力下降显著相关。BNs模型显示，高血压、受教育程度、工作状态和抑郁直接影响认知状态，而性格、运动、性别、阅读、收入和家庭地位有中等影响。此外，我们预测了AD可能的认知阶段，并使用因果推理和诊断推理模型分析了这些阶段的可能原因。 结论：BNs模型为认知功能障碍的因果分析和因果推理奠定了基础，老年人认知的预测模型可能有助于制定控制AD早期干预可改变危险因素的策略。

关键词: 认知评估，阿尔茨海默氏病，因果推理，贝叶斯网络模型，认知衰退，衰老。

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