Abstract
Dendrimers are highly branched three-dimensional macromolecules with a highly controlled structure, a single molecular weight, numerous controllable dendritic branches and peripheral functionalities, as well as the tendency to adopt an ellipsoid or spheroid shape once a certain size is reached. These features have made them attractive for application in pharmaceutical and medicinal chemistry in gene transfection, as medical imaging agents, and as drug carriers in potential drug delivery agents. The incorporation of metallic species into dendritic molecules has also been reported; the focus has been on organometallic dendrimers with metallic species only at specific positions of the molecules, such as the core, dendritic branches and the periphery, studied for their magnetic, electronic, and photo-optical or catalytic properties. Dendrimers have been investigated for optoelectronic applications (adsorption, emission, laser emission, nonlinear optics) through the encapsulation of active units by dendritic branches, core and peripheral. This review briefly discusses their use in nanomedicine, cancer treatment, treatment of other diseases, tissue repair, catalysis and applications in OLEDs and solar cells.
Keywords: Dendrimer, nanomedicine, catalysis, dendritic effects, solar cells, OLEDs.
Graphical Abstract
Current Organic Chemistry
Title:Dendrimer Applications: A Brief Review
Volume: 25 Issue: 11
Author(s): Luis Daniel Pedro-Hernández*Marcos Martínez-García
Affiliation:
- Instituto de Quimica, Universidad Nacional Autonoma de Mexico, Ciudad Universitaria, Circuito Exterior, Coyoacan, C.P. 04510, Ciudad de Mexico,Mexico
Keywords: Dendrimer, nanomedicine, catalysis, dendritic effects, solar cells, OLEDs.
Abstract: Dendrimers are highly branched three-dimensional macromolecules with a highly controlled structure, a single molecular weight, numerous controllable dendritic branches and peripheral functionalities, as well as the tendency to adopt an ellipsoid or spheroid shape once a certain size is reached. These features have made them attractive for application in pharmaceutical and medicinal chemistry in gene transfection, as medical imaging agents, and as drug carriers in potential drug delivery agents. The incorporation of metallic species into dendritic molecules has also been reported; the focus has been on organometallic dendrimers with metallic species only at specific positions of the molecules, such as the core, dendritic branches and the periphery, studied for their magnetic, electronic, and photo-optical or catalytic properties. Dendrimers have been investigated for optoelectronic applications (adsorption, emission, laser emission, nonlinear optics) through the encapsulation of active units by dendritic branches, core and peripheral. This review briefly discusses their use in nanomedicine, cancer treatment, treatment of other diseases, tissue repair, catalysis and applications in OLEDs and solar cells.
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Cite this article as:
Pedro-Hernández Daniel Luis*, Martínez-García Marcos, Dendrimer Applications: A Brief Review, Current Organic Chemistry 2021; 25 (11) . https://dx.doi.org/10.2174/1385272825666210525155816
DOI https://dx.doi.org/10.2174/1385272825666210525155816 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
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