摘要
背景:细菌纤维素(BC)及其衍生物是一种丰富的可再生天然成分来源,对生物医学和医学应用具有重要意义,但尚未得到充分开发。BC是一种高纯度、生物相容性和多功能的生物材料,可以单独使用或与聚合物和纳米颗粒等其他成分结合使用,以提供不同的结构组织和功能。本文简要介绍了BC水凝胶的研究现状,重点介绍了BC基复合水凝胶的制备及其在生物医学领域的应用,特别是在伤口敷料、组织工程支架和药物输送等方面的应用。 方法:通过回顾近年来有关该课题的文献,总结了近年来bc基复合水凝胶的制备及其在伤口敷料、组织工程和药物传递等生物医学应用方面的进展。 结果:BC复合水凝胶拓宽了BC的应用领域,开发出多种性能优良的BC基生物材料。bc基水凝胶在生物医学领域具有良好的生物相容性和广阔的应用前景。 结论:bc基复合水凝胶具有三维结构、无毒、纯度高、生物相容性好等优点,具有开发可持续、多功能生物医用材料的广阔前景。
关键词: 细菌纤维素(BC),水凝胶,生物医学应用,伤口愈合,组织工程支架,药物输送。
Current Medicinal Chemistry
Title:Biomedical Applications of Bacterial Cellulose based Composite Hydrogels
Volume: 28 Issue: 40
关键词: 细菌纤维素(BC),水凝胶,生物医学应用,伤口愈合,组织工程支架,药物输送。
摘要:
Background: Bacterial cellulose (BC) and its derivatives are a rich source of renewable natural ingredients, which are of great significance for biomedical and medical applications but have not yet been fully exploited. BC is a high-purity, biocompatible, and versatile biomaterial that can be used alone or in combination with other ingredients such as polymers and nanoparticles to provide different structural organization and function. This review briefly introduces the research status of BC hydrogels, focusing on the preparation of BC-based composite hydrogels and their applications in the field of biomedicine, particularly the wound dressings, tissue engineering scaffolds, and drug delivery.
Methods: By reviewing the most recent literature on this subject, we summarized recent advances in the preparation of BC-based composite hydrogels and their advances in biomedical applications, including wound dressings, tissue engineering, and drug delivery.
Results: BC composite hydrogels have broadened the field of application of BC and developed a variety of BC-based biomaterials with excellent properties. BC-based hydrogels have good biocompatibility and broad application prospects in the biomedical field.
Conclusion: BC-based composite hydrogels with the advantages of 3D structure, nontoxicity, high purity, and good biocompatibility, have great prospects in the development of sustainable and multifunctional biomaterials for biomedical applications.
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Cite this article as:
Biomedical Applications of Bacterial Cellulose based Composite Hydrogels, Current Medicinal Chemistry 2021; 28 (40) . https://dx.doi.org/10.2174/0929867328666210412124444
DOI https://dx.doi.org/10.2174/0929867328666210412124444 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
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