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Current Pharmaceutical Design

Editor-in-Chief

ISSN (Print): 1381-6128
ISSN (Online): 1873-4286

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Editorial

Development of Hydrogen Medicine and Biology: Potential for Various Applications in Diverse Fields

Author(s): Shigeo Ohta

Volume 27, Issue 5, 2021

Published on: 11 February, 2021

Page: [583 - 584] Pages: 2

DOI: 10.2174/138161282705210211144515

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Ohsawa I, Ishikawa M, Takahashi K, et al. Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals. Nat Med 2007; 13(6): 688-94.
[http://dx.doi.org/10.1038/nm1577] [PMID: 17486089]
[2]
Ohta S. Molecular hydrogen as a preventive and therapeutic medical gas: initiation, development and potential of hydrogen medicine. Pharmacol Ther 2014; 144(1): 1-11.
[http://dx.doi.org/10.1016/j.pharmthera.2014.04.006] [PMID: 24769081]
[3]
Nicolson GL, de Mattos GF, Settineri R, et al. Clinical effects of hydrogen administration: from animal and human diseases to exercise medicine. Int J Clin Med 2016; 07(01): 32-76.
[http://dx.doi.org/10.4236/ijcm.2016.71005]
[4]
Ohta S. Direct targets and subsequent pathways for molecular hydrogen to exert multiple functions: Focusing on interventions in radical reactions. Curr Pharm Des 2021; 27: 595-609.
[5]
Slezak J, Kura B, LeBaron TW, Singal PK, Buday J, Barancik M. Oxidative stress and pathways of molecular hydrogen effects in medicine. Curr Pharm Des 2021; 27(610): 610-25.
[6]
Radyuk SN. Mechanisms underlying the biological effects of molecular hydrogen. Curr Pharm Des 2021; 27: 625-35.
[7]
Zhang L, Yu H, Tu Q, He Q, Huang N. New approaches to hydrogen therapy of various diseases. Curr Pharm Des 2021; 27: 636-49.
[8]
Sano M, Tamura T. Hydrogen gas therapy: from preclinical studies to clinical trials. Curr Pharm Des 2021; 27: 650-8.
[9]
Ohsawa I. Biological responses to hydrogen molecule and its preventive effects on inflammatory diseases. Curr Pharm Des 2021; 27: 659-66.
[10]
Qi B, Yu Y, Wang Y, Wang Y. Yu, Xie K. Perspective of molecular hydrogen in the treatment of sepsis. Curr Pharm Des 2021; 27: 667-78.
[11]
Terasaki Y, Terasaki M, Shimizu A. Protective effects of hydrogen against irradiation. Curr Pharm Des 2021; 27: 679-86.
[12]
Noda M, Liu J, Jiangang Long J. Neuroprotective and preventive effects of molecular hydrogen. Curr Pharm Des 2021; 27: 585-91.
[13]
Domoki F. Hydrogen-induced neuroprotection in neonatal hypoxic-ischemic encephalopathy. Curr Pharm Des 2021; 27: 687-94.
[14]
Satoh Y. Potential of hydrogen for improving mental disorders and related diseases. Curr Pharm Des 2021; 27: 695-702.
[15]
Huang L, Lenahan C, Boling W, Tang J, Zhang JH. Molecular hydrogen application in stroke: bench to bedside. Curr Pharm Des 2021; 27: 703-12.
[16]
Qin S. Role of hydrogen in atherosclerotic diseases from bench to bedside. Cur Pharm Des 2021; 713-22.
[17]
Takahashi H. Application of Hydrogen in Ophthalmology. Curr Pharm Des 2021; 27: 592-4.
[18]
Ostojic SM. Hydrogen gas as an exotic performance-enhancing agent: challenges and opportunities. Curr Pharm Des 2021; 27: 723-30.
[19]
Jonatas E, Nogueira JE, Branco LGS. Recent advances in molecular hydrogen research reducing exercise-induced oxidative stress and inflammation. Curr Pharm Des 2021; 27: 731-6.
[20]
Bajgai J, Lee K-J. Rahman MdH, Fadriquela A, Kim C-S. Role of molecular hydrogen in skin diseases and its impact in beauty. Curr Pharm Des 2021; 27: 737-46.
[21]
Longna Li L, Lou W, Kong L, Shen W. Hydrogen commonly applicable from medicine to agriculture: from molecular mechanisms to the field. Curr Pharm Des 2021; 27: 747-59.

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