摘要
心血管疾病(CVD)目前占非传染性疾病的近一半。流行病学研究表明,富含蔬菜和水果的饮食对心血管具有保护作用。在此背景下,我们的研究结果证明了广泛食用的水果和蔬菜提取物的抗血小板活性,其中在我们的实验室工作中突出了番茄。番茄渣是番茄酱生产的主要副产品,由果皮和种子组成,是生物活性化合物的丰富来源。番茄渣具有强效的抗血栓形成作用,甚至比番茄还要大。鉴于大量工业生产的番茄渣,有机会利用这种副产品获得具有抗凝集和抗血栓形成特性的功能性产品,可用作健康食品中的添加剂,从而预防心血管疾病。本综述将重点关注血小板作为番茄渣中不同生物活性化合物抗血栓形成作用的靶点。
关键词: . 心血管疾病、血小板、抗血栓形成、血小板聚集、番茄渣、多酚、番茄红素。
图形摘要
Current Drug Targets
Title:Antiplatelet Effects of Bioactive Compounds Present in Tomato Pomace
Volume: 22 Issue: 15
关键词: . 心血管疾病、血小板、抗血栓形成、血小板聚集、番茄渣、多酚、番茄红素。
摘要: Cardiovascular diseases (CVD) currently account for nearly half of non-communicable diseases. Epidemiological studies have demonstrated the cardiovascular protective role of a diet rich in vegetables and fruits. In this context, our research outcomes have demonstrated the antiplatelet activities of fruits and vegetable extracts widely consumed, among which tomato was highlighted in our lab work. Tomato pomace, a major byproduct of tomato paste production, consists of skin and seeds and is a rich source of bioactive compounds. Tomato pomace has potent antithrombotic effects, even greater than the tomato. Given the large volumes of an industrial generation of tomato pomace, there is an opportunity to use this by-product to obtain a functional product with antiaggregant and antithrombotic properties that could be useful as an additive in health foods and thus prevent CVD. This review will focus on the platelet as the target for the antithrombotic actions exerted by the different bioactive compounds present in tomato pomace.
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Cite this article as:
Antiplatelet Effects of Bioactive Compounds Present in Tomato Pomace, Current Drug Targets 2021; 22 (15) . https://dx.doi.org/10.2174/1389450122999210128180456
DOI https://dx.doi.org/10.2174/1389450122999210128180456 |
Print ISSN 1389-4501 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-5592 |
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