A Short Review on the Synthesis of 1,2,4-Triazine Derivatives as Bioactive Compounds

Title:A Short Review on the Synthesis of 1,2,4-Triazine Derivatives as Bioactive Compounds

Volume: 18 Issue: 8

Author(s): Heba E. Hashem*

Affiliation:

• Department of Chemistry, Faculty of Women, Ain Shams University, Heliopolis, Cairo 11757,Egypt

Keywords: 1, 2, 4-Triazine, fused triazine, heterocycles, biological activity, synthesis, oxo derivatives.

Abstract: Triazines and their oxo derivatives are a representative class of heterocyclic compounds which have attracted great attention in organic synthesis and medicinal chemistry as they have been associated with a broad range of pharmacological activities. 1,2,4-Triazines and their oxo derivatives exhibit a broad range of biological activities, including antimicrobial, antifungal, anticancer, antiinflammatory, besides having importance in the dyes and pesticides field. This review presents the different methods of the synthesis of triazine/one derivatives. Also, this literature surveys the different effects of these compounds in pharmaceuticals.

Cite this article as:

Hashem E. Heba *, A Short Review on the Synthesis of 1,2,4-Triazine Derivatives as Bioactive Compounds, Mini-Reviews in Organic Chemistry 2021; 18 (8) . https://dx.doi.org/10.2174/1570193X18666210122154419