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当代阿耳茨海默病研究

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ISSN (Print): 1567-2050
ISSN (Online): 1875-5828

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Research Article

西班牙阿尔茨海默氏病患者书写障碍的演变

卷 17, 期 9, 2020

页: [845 - 857] 页: 13

弟呕挨: 10.2174/1567205017666201204162837

价格: $65

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摘要

背景：尽管一些研究表明写作困难可能是阿尔茨海默氏病（AD）的早期症状之一，但与口头语言相比，它们很少得到研究。特别值得一提的是，由于缺乏认知能力，纵向研究很少能观察到书写障碍。 目的：本研究的目的是检查AD患者的写作特征并监测其在随访期间的表现恶化。 方法：比较了64名参与者（一半的AD和一半的健康老年人）在单词和伪单词听写任务中的作用。在2.5年的随访期内，每6个月对患者进行一次评估。 结果：患者表现和错误状况的演变显示出一种典型的恶化模式，即词汇通路的早期损害，后来又扩展到语音通路，并最终影响周围过程。 结论：这些结果证实了从AD早期开始就存在写作困难，支持了该任务对早期诊断的价值

关键词: 阿尔茨海默氏病，写作障碍，认知能力下降，听写，拼写困难，纵向学习。

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[1]
Klimova b, Kuca K. Speech and language impairments in dementia. J Appl Biomed 2016; 14(2): 97-103.
[http://dx.doi.org/10.1016/j.jab.2016.02.002]
[2]
Fukui T, Lee E. Progressive agraphia can be a harbinger of degenerative dementia. Brain Lang 2008; 104(3): 201-10.
[http://dx.doi.org/10.1016/j.bandl.2007.10.005] [PMID: 18068758]
[3]
Croisile B. Writing, aging and Alzheimer’s disease. Psychol Neuropsychiatr Vieil 2005; 3(3): 183-97.
[PMID: 16126471]
[4]
Ellis AW. Spelling and writing (and reading and speaking) Normality and pathology in cognitive functions. London: Academic Press 1982; pp. 113-46.
[5]
Groves-Wright K, Neils-Strunjas J, Burnett R, O’Neill MJ. A comparison of verbal and written language in Alzheimer’s disease. J Commun Disord 2004; 37(2): 109-30.
[http://dx.doi.org/10.1016/j.jcomdis.2003.08.004] [PMID: 15013729]
[6]
Hughes JC, Graham N, Patterson K, Hodges JR. Dysgraphia in mild dementia of Alzheimer’s type. Neuropsychologia 1997; 35(4): 533-45.
[http://dx.doi.org/10.1016/S0028-3932(96)00102-9] [PMID: 9106281]
[7]
Rapcsak SZ, Arthur SA, Bliklen DA, Rubens AB. Lexical agraphia in Alzheimer’s disease. Arch Neurol 1989; 46(1): 65-8.
[http://dx.doi.org/10.1001/archneur.1989.00520370067021] [PMID: 2910263]
[8]
Folstein MF, Folstein SE, McHugh PR. “Mini-mental state”. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975; 12(3): 189-98.
[http://dx.doi.org/10.1016/0022-3956(75)90026-6] [PMID: 1202204]
[9]
Cuetos F, Martinez T, Martinez C, Izura C, Ellis AW. Lexical processing in Spanish patients with probable Alzheimer’s disease. Brain Res Cogn Brain Res 2003; 17(3): 549-61.
[http://dx.doi.org/10.1016/S0926-6410(03)00169-1] [PMID: 14561444]
[10]
Rodríguez-Ferreiro J, Martínez C, Pérez-Carbajal A-J, Cuetos F. Neural correlates of spelling difficulties in Alzheimer’s disease. Neuropsychologia 2014; 65(0): 12-7.
[http://dx.doi.org/10.1016/j.neuropsychologia.2014.10.006] [PMID: 25447060]
[11]
Luzzatti C, Laiacona M, Agazzi D. Multiple patterns of writing disorders in dementia of the Alzheimer type and their evolution. Neuropsychologia 2003; 41(7): 759-72.
[http://dx.doi.org/10.1016/S0028-3932(02)00328-7] [PMID: 12631527]
[12]
Eustache F, Lambert J. Neuro-cognitive models of spelling and Alzheimer disease: mutual clarification. Rev Neurol (Paris) 1996; 152(11): 658-68.
[PMID: 9033940]
[13]
Lambert J, Giffard B, Nore F, de la Sayette V, Pasquier F, Eustache F. Central and peripheral agraphia in Alzheimer’s disease: From the case of Auguste D to a cognitive neuropsychology approach. Cortex 2007; 43(7): 935-51.
[http://dx.doi.org/10.1016/S0010-9452(08)70692-0] [PMID: 17941351]
[14]
Silveri MC, Corda F, Di Nardo M. Central and peripheral aspects of writing disorders in Alzheimer’s disease. J Clin Exp Neuropsychol 2007; 29(2): 179-86.
[http://dx.doi.org/10.1080/13803390600611351] [PMID: 17365253]
[15]
Neils J, Roeltgen DP, Greer A. Spelling and attention in early Alzheimer’s disease: Evidence for impairment of the graphemic buffer. Brain Lang 1995; 49(3): 241-62.
[http://dx.doi.org/10.1006/brln.1995.1032] [PMID: 7640965]
[16]
Cortese MJ, Balota DA, Sergent-Marshall SD, Buckner RL. Spelling via semantics and phonology: Exploring the effects of age, Alzheimer’s disease, and primary semantic impairment. Neuropsychologia 2003; 41(8): 952-67.
[http://dx.doi.org/10.1016/S0028-3932(02)00320-2] [PMID: 12667531]
[17]
Aarsland D, Høien T, Larsen JP, Oftedal M. Lexical and nonlexical spelling deficits in dementia of the Alzheimer type. Brain Lang 1996; 52(3): 551-63.
[http://dx.doi.org/10.1006/brln.1996.0029] [PMID: 8653395]
[18]
Pestell S, Shanks MF, Warrington J, Venneri A. Quality of spelling breakdown in Alzheimer’s disease is independent of disease progression. J Clin Exp Neuropsychol 2000; 22(5): 599-612.
[http://dx.doi.org/10.1076/1380-3395(200010)22:5;1-9;FT599] [PMID: 11094395]
[19]
Croisile B, Ska B, Brabant MJ, et al. Comparative study of oral and written picture description in patients with Alzheimer’s disease. Brain Lang 1996; 53(1): 1-19.
[http://dx.doi.org/10.1006/brln.1996.0033] [PMID: 8722896]
[20]
Platel H, Lambert J, Eustache F, et al. Characteristics and evolution of writing impairment in Alzheimer’s disease. Neuropsychologia 1993; 31(11): 1147-58.
[http://dx.doi.org/10.1016/0028-3932(93)90064-7] [PMID: 8107977]
[21]
McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM. Clinical diagnosis of Alzheimer’s disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer’s Disease. Neurology 1984; 34(7): 939-44.
[http://dx.doi.org/10.1212/WNL.34.7.939] [PMID: 6610841]
[22]
Galdós L, Manubens JM. Historia clínica, exploración física y neurológica y pruebas complementarias Guías en Demencias Conceptos, criterios y recomendaciones para el estudio del paciente con demencia Grupo de Estudio de Neurología de la Conducta y Demencias de la Sociedad Española de Neurología. Barcelona: Masson 2000.
[23]
Reisberg B, Ferris SH, de Leon MJ, Crook T. The Global Deterioration Scale for assessment of primary degenerative dementia. Am J Psychiatry 1982; 139(9): 1136-9.
[http://dx.doi.org/10.1176/ajp.139.9.1136] [PMID: 7114305]
[24]
Sebastián N, Martí MA, Carreiras MF, Cuetos F. LEXESP, Léxico informatizado del español. Barcelona: Ediciones de la Universitat de Barcelona 2000.
[25]
Pérez MA, Alameda JR, Cuetos F. Frecuencia, longitud y vecindad ortográfica de las palabras de 3 a 16 letras del Diccionario de la Lengua Española” (RAE, 1992). Revista Electrónica de Metodología Aplicada 2003; 8: 1-10.
[26]
Croisile B, Brabant MJ, Carmoi T, Lepage Y, Aimard G, Trillet M. Comparison between oral and written spelling in Alzheimer’s disease. Brain Lang 1996; 54(3): 361-87.
[http://dx.doi.org/10.1006/brln.1996.0081] [PMID: 8866054]
[27]
Beeson MP, Rapcsak SZ, Plante E, et al. The neural substrates of writing: A functional magnetic resonance imaging study. Aphasiology 2003; 17: 647-65.
[http://dx.doi.org/10.1080/02687030344000067]
[28]
Patterson KE, Kay J. Letter-by-letter reading: Psychological descriptions of a neurological syndrome. Q J Exp Psychol 1982; 34(A): 411-1.
[29]
Rapcsak SZ, Rubens AB, Laguna JF. From letters to words: Procedures for word recognition in letter-by-letter reading. Brain Lang 1990; 38(4): 504-14.
[http://dx.doi.org/10.1016/0093-934X(90)90134-3] [PMID: 2375979]

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