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Review Article

Colorectal Cancer Epidemiology: Recent Trends and Impact on Outcomes

Author(s): Firas Baidoun, Kholoud Elshiwy, Yasmine Elkeraie, Zahi Merjaneh, George Khoudari, Muhammad Talal Sarmini, Mohamed Gad, Muneer Al-Husseini and Anas Saad*

Volume 22, Issue 9, 2021

Published on: 17 November, 2020

Page: [998 - 1009] Pages: 12

DOI: 10.2174/1389450121999201117115717

Price: $65

Abstract

Colorectal cancer (CRC) is the third most common cancer and the second leading cause of cancer related deaths in the world with an estimated number of 1.8 million new cases and about 881,000 deaths worldwide in 2018. The epidemiology of CRC varies significantly between different regions in the world as well as between different age, gender and racial groups. Multiple factors are involved in this variation, including risk factor exposure, demographic variations in addition to genetic susceptibility and genetic mutations and their effect on the prognosis and treatment response. In this mini-review, we discuss the recent epidemiological trend including the incidence and mortality of colorectal cancer worldwide and the factors affecting these trends.

Keywords: Colorectal cancer, epidemiology, incidence, mortality, demographic, prognosis.

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Graphical Abstract

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