摘要
高强度聚焦超声(HIFU)是一种无创的治疗恶性肿瘤的方法。本文就HIFU在乳腺癌治疗中的临床应用现状作一综述。除了临床研究,本综述还将探讨一些基础研究,这些研究可能解决与此模式相关的技术问题。一般来说,HIFU被认为是非侵入性和非电离性的,是安全的。并发症发生率低,可重复治疗,对部分患者具有吸引力。然而,自20多年首次用于治疗乳腺癌以来,HIFU的临床研究仍处于研究阶段,仅在几个中心可用。HIFU研究较少的原因包括缺乏专业的医疗团队和生物工程技术人员,以及乳腺癌专用的成像-HIFU平台无法取得积极的结果。尽管有这些情况,我们相信在不久的将来,HIFU将最终成为大多数乳腺癌患者的治疗选择。
关键词: 高强度聚焦超声,治疗性超声,消融术,图像引导,无创方式,乳腺癌。
Current Medicinal Chemistry
Title:High-Intensity Focused Ultrasound in the Treatment of Breast Cancer
Volume: 28 Issue: 25
关键词: 高强度聚焦超声,治疗性超声,消融术,图像引导,无创方式,乳腺癌。
摘要: High-intensity focused ultrasound (HIFU) is a non-invasive method of ablating malignant tumors. This paper will review the current clinical application of HIFU specially in the treatment of breast cancer. In addition to clinical studies, this review will also look into some basic studies that could address the technical issues related to this modality. In general, HIFU is considered to be safe being non-invasive and non-ionizing. The complication occurrence rate is low and repeated treatment is possible, making it an attractive option for some patients. However, for more than two decades since it was first used to treat breast cancer, clinical studies on HIFU still remain at the investigative stage and are only available in several centers. Reasons contributing to such few studies on HIFU include lack of specialized medical team and bioengineering technical staff, and breast cancer-dedicated imaging-HIFU platform to attain positive outcomes. Despite these circumstances, we believe that HIFU will eventually become the treatment of choice for most breast cancer patients in the near future.
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Cite this article as:
High-Intensity Focused Ultrasound in the Treatment of Breast Cancer, Current Medicinal Chemistry 2021; 28 (25) . https://dx.doi.org/10.2174/0929867327666201111143206
DOI https://dx.doi.org/10.2174/0929867327666201111143206 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
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